Not exact matches
While top - down channels are used to communicate vision and strategy in order to get policies and processes aligned with them, bottom - up processes are necessary too, in order for leaders to be aware
of the issues faced at the
lower levels, as well as to measure the
impact of the policies and practices implemented.
But that means there's a whole group
of middle and
lower -
level managers without leadership experience — and their lack
of training has a serious
impact.
Actual results, including with respect to our targets and prospects, could differ materially due to a number
of factors, including the risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in higher production costs and
lower margins; our ability to
lower costs; the risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on additional capacity on a timely basis to meet customer demand; the risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively
impact demand for our products; product mix; risks associated with the ramp - up
of production
of our new products, and our entry into new business channels different from those in which we have historically operated; the risk that customers do not maintain their favorable perception
of our brand and products, resulting in
lower demand for our products; the risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant additional costs, including costs associated with warranty returns or the potential recall
of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability
of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments; risks resulting from the concentration
of our business among few customers, including the risk that customers may reduce or cancel orders or fail to honor purchase commitments; the risk that we are not able to enter into acceptable contractual arrangements with the significant customers
of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits
of the transaction; the risk that retail customers may alter promotional pricing, increase promotion
of a competitor's products over our products or reduce their inventory
levels, all
of which could negatively affect product demand; the risk that our investments may experience periods
of significant stock price volatility causing us to recognize fair value losses on our investment; the risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity
of raw materials, subsystems and finished products with the required specifications and quality; the risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired; risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization
of products under development, such as our pipeline
of Wolfspeed products, improved LED chips, LED components, and LED lighting products risks related to our multi-year warranty periods for LED lighting products; risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development
of new technology and competing products that may impair demand or render our products obsolete; the potential lack
of customer acceptance for our products; risks associated with ongoing litigation; and other factors discussed in our filings with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.
Growth strategies resemble a kind
of ladder, where
lower -
level rungs present less risk but maybe less quick - growth
impact.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect
of lowering prices or reducing the number
of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the
levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange
impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Risks associated with the Consumer Discretionary sector include, among others, apparel price deflation due to
low - cost entries, high inventory
levels and pressure from e-commerce players; reduction in traditional advertising dollars; increasing household debt
levels that could limit consumer appetite for discretionary purchases; declining consumer acceptance
of new product introductions; and geopolitical uncertainty that could
impact consumer sentiment.
They also believe that flexible work would save them money (85 %), help them be healthier (89 %),
lower their stress
levels (89 %), and either provide a huge improvement (51 %) or positive
impact (48 %) to their quality
of life.
Both increases were due to net inflows to long - term and liquidity products, partially offset by the
impact of lower market
levels.
The
low impact nature
of our workout makes Pure Barre accessible to clients spanning a wide range
of ages and fitness
levels.
«However, historically high
levels of household debt and
low wage growth will offset some
of the positive
impact of recent strong employment data, so consumers are likely to remain cautious.»
Thereafter, the positive
impact of the higher
level of nominal GDP and the saving measures more than offset the fiscal cost
of the policy initiatives, resulting in
lower deficits than those forecast in the October 2010 Update to 2014 - 15, and a somewhat higher surplus in 2015 - 16.
It's a combination — it's the — it's both the adverse
impact of lower expected sub
levels and the adverse
impact of the stronger dollar.
If we are unable to reduce and / or maintain a sufficiently
low level of costs for designing, manufacturing, marketing, selling and distributing and servicing our electric vehicles relative to their selling prices, our operating results, gross margins, business and prospects could be materially and adversely
impacted.
The company's unchanged coal production guidance includes the largely offsetting
impacts of Glencore's acquisition
of Rio Tinto's 82 % interest in the Hail Creek mine, in Australia, and
lower production from Prodeco in 2018, before returning to higher
levels in 2019.
«
Lower wealth
levels, as well as more limited access to capital,
impact the ability
of minority - owned firms to thrive.»
The representatives from Harford County Climate Action made it clear — human activity, primarily the burning
of fossil fuels, has had a clear and measurable
impact on the Earth's climate over the last century, and those actions have put
low - lying areas
of Harford County in danger from rising sea
levels.
Companies with
low levels of automation must identify, streamline and automate high -
impact business processes.
After declining to
low levels in 1997, consumers» inflation expectations, as surveyed by the Melbourne Institute, increased slightly in the first half
of this year, most probably in anticipation
of the
impact of the
lower Australian dollar on prices.
Whether inflation rises or the Federal Reserve Bank uses its power over interest rates to limit the potential inflationary
impact of the falling dollar, the ultimate outcome
of our recent overdependence on foreign saving will be a
lower standard
of living (or slower increases in living standards), such that decent
levels of retirement income (private and public) can not be maintained.
The first study on the relationship between a
low carb diet and cholesterol was done in 1981 and was monitoring the
impact of a ketogenic diet and the cholesterol
levels.
As the result from the study shows the glucose
levels might increase if having caffeine together with a meal with a high amount
of carbohydrates but there is no indication what the
impact is for people who eat according to a
low carb diet.
In general berries and granny smith apples are
lower glycemic fruit that has less
of an
impact on your blood sugar
levels.
By developing only
low -
impact philosophies, ROELMI HPC offers innovative technologies and customized solutions, aimed to reach the highest
level of quality, controlling the activity and respecting customers» safety.
For brand owners who want consistent drop -
impact toughness in their dual ovenable trays, Elvaloy ® resins are premium compatibilizers that, when combined with Elvaloy ® AC or similar resins, provide the desired
level of low - temperature PET toughness in refrigerated and frozen meals.
«In fact studies show that consuming products that contain coconut flour can help to
lower the overall glycemic
impact of the food and to support stable blood sugar
levels» (source).
Playing in the
lower levels of French football, the player made an instant
impact at Arsenal by getting himself sent off on his debut.
Forget the quality
of opposition etc and other churlish remarks but our attacking boys done good; Ramsey for Wales, Welbz for England, Alexis for Chile, Mesut for Germany — brief but bright cameos from Santi and Ollie, appearances for Theo and Poldi (
Low has him inked in as an 80 min
impact guy — easier to do in an international setting than at club
level).
Whilst a lot
of the media discussion from Week 4
of the Premier League has revolved around boring games, the
low level of goals scored so far, and even the amount
of time that the ball is actually in play, it's actually been a very busy weekend for the Manager
Impact Index with Villas Boas, David Moyes and Michael Laudrup being the stand out performers this week.
One way, I believe, to address the problem
of under - reporting and increase the chances a concussion will be identified early on the sports sideline may be to rely less on athletes themselves to remove themselves from games or practices by reporting concussion symptoms (which the most recent study shows occurs at a shockingly
low rate, [9] or on game officials and sideline observers to observe signs
of concussion and call for a concussion assessment, but to employ technology to increase the chances that a concussion will be identified by employing
impact sensors designed to monitor head
impact exposure in terms
of the force
of hits (both linear and rotational), number, location, and cumulative
impact, in real time at all
levels of football, and in other helmeted and non-helmeted contact and collision sports, where practical, to help identify high - risk
impacts and alert medical personnel on the sideline so they can consider performing a concussion assessment.
We know that
low levels of iron have a subtle and irreversible
impact on motor skills, problem solving, and even emotional regulation.
What they found was that fathers»
level of education has the biggest
impact on the likelihood
of low educational attainment — itself (see below) a key factor behind poverty.
Mothers» education
level has an
impact too, but to a lesser degree; people are around 3 times more likely to have a
low educational outcome if their mother has a
low level of education.
From his youth sports experiences in Evanston, Wyo., to stepping onto Lambeau Field, he's experienced the highs and
lows of competition at all
levels and knows first - hand the life - shaping
impact coaches can have on kids» lives.
A major risk factor is premature birth and
low birthweight, conditions which
impact more than half
of multiples on some
level.
According to the study's abstract, this study is the first
of its kind to examine how
low - income families» needs for diapers
impacts them on psychosocial
levels.
Another example
of how friendly bacteria
impact obesity
levels is that
of gut bacteria: obese people are seen to have
lower levels of the friendly gut bacteria than normal weight people have in their digestive tract.
«Even with very
low levels, these chemicals can have a major
impact on a child's body because they are rapidly developing and weigh so little,» which means their bodies are generally less capable
of eliminating toxins.
Much
of frontline policing is taken up with
low level anti-social behaviour, which has a big
impact on the quality
of life
of Londoners, but is not always best dealt with by the Met.
Gillibrand said Sunday that she sent a letter to Sessions inviting him to talk about the
impacts the War on Drugs has had on New York's black and Latino communities with constituents who are denied jobs, housing and college financial aid because
of nonviolent,
low -
level pot arrests.
Apparently, this translates to «Comments
of the Institute for Energy and Environmental Research on the Department
of Energy's Notice
of Intent to Prepare an Environmental
Impact Statement for the Disposal
of Greater - Than - Class - C
Low -
Level Radioactive Waste» (not much
of an improvement, though it makes perfect sense for those In The Know).
«I look at this through lens
of young black and Latino men whose lives have been unfortunately
impacted disproportionally as a result
of possessing
low levels of marijuana,» she said at a press conference outside
of New York State Supreme Court in
Lower Manhattan.
And the
impact of the proposal, announced by Cuomo today at a New York City union rally also attended by Vice President Joe Biden, wouldn't necessarily be limited to the
lowest -
level unskilled service jobs.
Legislator Casey Jordan took up the measure and said the Senate's bill would require funding
of any state program or expenditure item that
impacts lower levels of government, to be paid for by the state.
In a move aimed at dampening the
impact of «broken windows» policing, the New York City Council passed bills to create a civil process for some
of the most common
low -
level infractions observed by police officers, including public drinking and public urination.
The new study lays out a toolkit for understanding a series
of simple,
low - cost interventions that can be adapted and planned at a local
level to minimise the
impact of traffic.
The changes came after labor unions raised issues with the initial version
of the amendment, which they said was far too broad in its scope and could
impact lower level civil servants.
«A modest reduction in flows at Hinckley right now will alleviate any further threat from current
low levels and the potential
impact of the warm - weather months to come.
If you're going to criticize the educational
level of minorities, I'm wondering why other groups get high
level policy positions that
impact on the lives
of most Americans with
low levels of education.
«For any economic recovery to be meaningful, it must positively
impact on the lives
of the people at the
lower level,» he stated.
«I look at this through the lens
of reinvesting in communities that have historically been ignored, and I look at this through the lens
of young black and Latino men whose lives unfortunately have been
impacted disproportionately as a result
of possessing
low levels of marijuana,» she said.