Sentences with phrase «low measures of uncertainty»

In metrology, measuring sticks must be traceably calibrated against standard tools of measurement, which must further be traced to primary standards based on physical constants, such as units of wavelength of light that have low measures of uncertainty.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

But «it is likely that the uncertainty surrounding the presidential election had a negative impact, especially among lower income consumers, and without that added uncertainty, the confidence measures may not have weakened,» said Richard Curtin, the leading economist of the University of Michigan's preliminary consumer confidence survey.

Institutional investors may be scratching their heads at why the widely watched measure of market concern known colloquially as the «fear index,» or VIX, recently reached a 23 - year low despite plenty of reasons for the sort of uncertainty that makes markets jittery.

A: Every investor will have to make their own judgment about the market, it does seem like measures of volatility are relatively low given all the uncertainties at present.

The GALLEX experiment measures a low flux of solar neutrinos, but with such large uncertainties that, again, theresult could be consistent with the predictions of the new solar models.

Based on the rather vast uncertainties in aerosol forcing, and the substantial discrepancies between model projections of ocean heat uptake and measured heat uptake (ARGO), it strikes me as bizarre that the IPCC insists on excluding the possibility of quite low sensitivity, when there is a wealth of evidence for fairly low sensitivity.

It's correct to take the precautionary principle into account in the estimate of the damages giving more weight to the unfavorable outcomes than to the favorable, but the uncertainties in the efficiency of the mitigating measures should be also taken into account and taken them into account means that the correct level of tax is lower than it would be without this uncertainty.

The shading indicates a measure of uncertainty about future sea level for two different scenarios — a low emissions scenario where carbon emissions are rapidly cut (blue RCP 2.6) and a high emissions scenario with no carbon cuts (red RCP 8.5).

The hope of the industry was that RSD would provide a rapidly deployable method for measuring power performance that would also result in a lower uncertainty due to having measurements across the entire turbine rotor.

The first big issue is about the accuracy of estimations: (a) there are discordant trends of present: low atmospheric satellite measured temperature vs. GST measured in land & oceans; (b) there is a big uncertainty linked to the proxy data obtained during XX, XIX and beyond centuries.