In multiple studies involving aging men, low testosterone levels are associated with
lower skeletal muscle mass, muscle strength, physical function, bone mineral density and higher risk of fractures and death.
Not exact matches
Symptoms and signs of
low testosterone include decreasing lean body
mass or
skeletal muscle with increased body fat; fatigue, decreased energy, motivation and drive; decreased sex drive (libido) and erectile dysfunction; brain fog or reduced concentration or mental focus; mood changes including depression, anxiety or irritability; decreased bone density; and hair loss.
Low levels of myostatin protein are desirable because it leads to increased ability to build
skeletal muscle mass.
Results: Compared with physical activity and placebo, supplementation plus physical activity increased fat - free
mass (1.7 - kg gain, P < 0.001), relative
skeletal muscle mass (P = 0.009), android distribution of fat (P = 0.021), handgrip strength (P = 0.001), standardized summary scores for physical components (P = 0.030), activities of daily living (P = 0.001), mini nutritional assessment (P = 0.003), and insulin - like growth factor I (P = 0.002), and
lowered C - reactive protein (P = 0.038).
This is consistent with reports associating regular exercise with reduced incidence of dementia3 and several cancer types.26 - 28 Potential reasons for improved functional status and survival among regular exercisers may include increased cardiovascular fitness and improved aerobic capacity and organ reserve,29 - 31 increases in
skeletal mass and metabolic adaptations of
muscle with decreased frailty,29 - 31
lower levels of circulating inflammatory markers, 32 improved response to vaccinations, 33 and improved higher - order cognitive functions.34