Significantly, the effect of PARTICLE in limiting the time and extent of the radiation - induced increase in DNA methylation is more pronounced at
lower radiation doses than at higher doses.
Scientists used those data to extrapolate how many excess cancer cases would develop at
lower radiation doses.
CCTA can capture the full anatomic map of the coronary arteries in a single heartbeat with
low radiation dose.
They have to piece together such molecular data to reveal whether cell circuitry is disrupted at
low radiation doses.
VetCAT scans have a significantly
lower radiation dose than full - body scanners in the hospital.
Not exact matches
The effects of extended exposure to
radiation, however
low the
dose, were still unknown.
Diagnostic Radiology at Boston Children's is designed to facilitate high - quality and rapid x-ray examinations using the
lowest possible
radiation doses for your child, no matter her size, age or medical condition.
But scientists still don't know how the human body will react to sustained
low - level
doses of
radiation inherent in space travel.
Japanese researchers are about to launch one of the most ambitious epidemiological studies ever attempted on the effects of
low -
dose radiation.
A new screening tool for prostate cancer, the prostate - specific antigen test, enabled doctors to detect it earlier in more men, and patients were flocking to hospitals for
low doses of conventional photon
radiation.
APRIL 1960
RADIATION — «With the new measurement of the mean lethal
dose for reproductive function of mammalian cells, it is now possible to explain the relatively
low mean lethal
dose of 400 to 500 roentgens for the entire body.
Previous studies also demonstrate that moderate hypo - fractionated
radiation therapy (HRT), consisting of daily treatment for one month using a larger
dose per treatment, provides a similar
low risk of recurrence, and may even be
lower with HRT than CRT.
«Our preclinical data suggest that combining
low doses of these inhibitors will enhance the clinical effects of both drugs as a potential treatment for patients with AML,» says the senior author, Feyruz V. Rassool, PhD, associate professor of
radiation oncology at the University of Maryland School of Medicine (UM SOM) and a researcher at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center (UMGCCC).
Johns Hopkins scientists report that rats exposed to high - energy particles, simulating conditions astronauts would face on a long - term deep space mission, show lapses in attention and slower reaction times, even when the
radiation exposure is in extremely
low dose ranges.
Even though
radiation from body scanners is likely to be very
low, the
doses should still be confirmed using dosimeters
The early cleanup workers faced a higher
dose, with the risk of acute
radiation sickness, resulting in nausea,
low blood cell counts and neurological issues.
The imaging software — developed and currently in use only at Cincinnati Children's — mathematically determines the
lowest possible
radiation dose for the patient before a scan is performed, according to the study led by David Larson, MD, radiology quality and safety director at the medical center and principal architect of the technology.
«The lotus is so robust that it can sprout after centuries of exposure to
low -
dose gamma
radiation,» Shen - Miller observes.
«Image quality is what determines the appropriate
radiation dose — the challenge is to find the threshold where the
dose is as
low as possible, but the images are still clear,» Larson added.
Mammography machines also use
low doses of
radiation.
Presenting these results at the 3rd ESTRO Forum in Barcelona, Spain, today (Monday) Professor James Morris, from the Department of
Radiation Oncology, Vancouver Cancer Centre, British Columbia Cancer Agency (BCCA), Vancouver, Canada, will say that the ASCENDE - RT1 trial is the first and only existing trial comparing
low -
dose - rate prostate brachytherapy (LDR - PB) for the curative treatment of prostate cancer with any other method of
radiation therapy delivery.
John Hemminger, a chemist from the University of California, Irvine, and chair of DOE's Basic Energy Sciences Advisory Committee, noted that within biological and environmental research, the Republican bill specifically favors research on biological systems, genomics, and the effects of
low -
dose radiation.
«Chronic exposure to
low -
dose radiation at Chernobyl favors adaptation to oxidative stress,» is published in Functional Ecology on Friday 25 April 2014.
So if biologists can discover how to disable cancer cells» DNA repair proteins, it may be possible to destroy tumours using
lower doses of
radiation or drugs.
Compounds based on RK - 33, he says, might have value in treating a broad array of cancers that highly express DDX33 or as a supplement to
radiation, making conventional
doses more effective or improving the killing ability of
lower doses.
Surprisingly,
low -
dose radiation takes longer for the body to repair than damage from high
doses does.
If these could be targeted to tumours — by attaching them to antibodies that recognise cancer cells, for instance — it would then be possible to destroy the malignant cells» DNA using
lower doses of
radiation or drugs.
Patients who received the highest
radiation doses had a risk of stomach cancer nearly threefold greater than patients who received the
lowest doses.
This determined that the
dose - effect relationship is linear down to the
lowest doses such that there is no safe
dose of
radiation, only permissible
doses.
«This study draws attention to the common consensus that the use of
low -
dose CT scans for image guidance for children is important for quality treatment and to ensure treatment accuracy,» said Stephanie A. Terezakis, MD, co-author of the study and assistant professor of
radiation oncology and molecular
radiation sciences at Johns Hopkins Sidney Kimmel Comprehensive Cancer Center in Baltimore.
«New cellular response to
radiation exposure: Must we reconsider the risks of
low doses?.»
Biophysical studies have shown that the damage arising to cells from an exposure to ionizing
radiation declines in a linearly manner with decreasing
dose, with some damage still occurring even at the
lowest doses.
This challenge to the established LNT model and raises questions on some of the basic assumptions used to assess the risk of
low dose radiation exposures.
«I think the jury is still out on what
low -
dose radiation does in terms of reproductive health outcomes,» says Grajewski.
This linear no - threshold (LNT)
dose - response relationship has been used to extrapolate the risks of
low doses of
radiation from epidemiological studies that were done following exposure to much higher
doses of
radiation (e.g. survivors of the atomic bombings).
«This device can help technologists and radiologists achieve the
radiation dose goal of ALARA, As
Low As Reasonably Achievable, while enhancing the quality and consistency of X-ray images,» Dr. Don said.
But such
doses are still relatively
low (see «Fear is the killer: Nuclear expert reveals
radiation's real danger «-RRB-.
We know surprisingly little about what
low -
dose radiation does to organisms and ecosystems.
Orthopaedic surgery and radiology collaborators have also implemented intraoperative use of
low -
dose protocols on fluoroscopy machines, which reduces
radiation exposure to both patients as well as physicians and staff in the operating room.
There is general recognition that procedural ionizing
radiation doses should be kept as
low as reasonably achievable.
Steve Wing, an epidemiologist from the University of North Carolina, Chapel Hill, points out that even the
low levels of
radiation that remain in the environment could be significant in the long run «because so many more people are exposed, even though the
dose per person decreases farther from the plant.»
To learn more, however, the mouse work should be repeated with
lower doses of
radiation, Saran says.
Considerable previous research in cell cultures has demonstrated that
low doses of ionizing
radiation results in «bystander» effects, in which nearby, unexposed tissues suffer cell death, mutations, and tumor - inducing growth (ScienceNOW, 7 September 2005).
The British government's chief adviser on
radiation is urging
lower dose limits for workers and the public in the light of a recent review of the dangers posed by
radiation.
He suggests that current estimates of cancer risk from
low doses of
radiation — say, from naturally occurring radon and diagnostic tests — may underestimate the danger by failing to take into account bystander effects.
The total
radiation delivered, 0.5 gray (Gy), was high relative to environmental levels (from sources such as naturally occurring radon in rock), but significantly
lower than equivalent human
doses experienced in CAT - scans or cancer therapy.
«If we can identify similar genetic loci in people, and if we could find biomarkers for these gene - environment interactions, then perhaps we could develop a simple blood test that identifies people who are at high risk of cancer from
low -
dose radiation,» says Mao.
They found that
low -
dose radiation didn't change the risk of cancer in most mice.
These genome - environment interactions only become significantly pronounced when the mouse is challenged by
low -
dose radiation.
Half of the mice were then exposed to a single, whole - body,
low dose of
radiation.