CrPV is substantially more virulent than FHV in Drosophila; injection of CrPV at much
lower titers resulted in mortality of 70 % of WT flies by 15 dpi.
All vaccine groups exhibited
lower titers or no detectable virus on day two after challenge.
Difficult - To - Express Proteins: Resolving Bioprocessing Challenges with a Scalable Perfusion Bioreactor Scott Waginer, Emily Wozniak, and Kyle Biesecker (The Cell Culture Company) Among some other recombinant glycoproteins, bi - and tri-specific antibodies are labeled as «difficult - to - express» proteins because of
low titers and sensitivity to environmental conditions.
The human like T cell epitopes may contribute to the delayed,
low titer of H7N9 hemagglutination inhibiting antibody responses and diminished seroconversion rates that have been observed in human infections and unadjuvanted H7 HA vaccination clinical trials.
If negative, they may not have to avoid the food groups containing those antigens.3 Low - to - undetectable IgG reactivity to the panel of 88 dietary antigens may indicate
a low titer of total IgG, or immune tolerance to the listed food groups.
The author also commented that «most cats with heartworm disease are antigen negative because of
low titers.»
Low titers indicate a small amount of coronavirus antibodies in the serum, while high titers indicate greater amounts of antibodies.
Most cats with heartworm disease are antigen negative because of
low titers.2
Low titers indicate a small amount of coronavirus antibodies, while high titers indicate much greater amounts of antibodies.
It is common for them to have
low titers to Valley Fever.
Immunity can not be assumed during the puppy vaccination series until approximately 2 weeks after using a high titer vaccine at 12 weeks of age or
a lower titer vaccine at 16 weeks of age PLUS a 5 day to 14 day period to allow the immune system to respond.
2)
Low titer — People and animals who live in the Sonoran Desert are exposed to the spores all the time.
Even though he recommends that the titer level be 1:100, he does not recommend re-vaccination unless there's a really
low titer.
Not exact matches
A certain percentage of men with zero viral
titers in their blood will still have very
low levels of virus in their semen.
The two schedules alternating AS03 - and MF59 - adjuvanted formulations led to
lower geometric mean (average)
titers (GMTs) than the group induced by two AS03 - adjuvanted formulations but higher GMTs than two doses of MF59 - adjuvanted formulation.
Low levels of antibody did not enhance disease, intermediate levels exacerbated disease, and high antibody
titers protected against severe disease.
In our study, 2 of 81, or 2.5 % of random adult blood donors exhibited borderline
titers of neutralizing antibody to TMAdV, indicating either a
low prevalence of TMAdV in the human population or cross-reactivity to a related virus (although no evidence of cross-reactivity was found with HAdV serotypes 1 through 35).
Overgrown cultures stimulate quiescence, the resting phase of the cell cycle; quiescent cells do not take up nucleic acid or express transgenes as well as actively dividing cells resulting in
lower lentiviral
titers.
Although safer, this system may be more cumbersome to use and lead to
lower viral
titers due to higher plasmid number.
High concentrations of Ab at birth were associated with
lower postimmunization
titers for tetanus and pneumococcus, but this association was not observed with H. influenzae type B or pertussis.
All groups given the S protein vaccine (SV) yielded virus after challenge and the differences between groups were significant (p = 0.002 for all groups, p = 0.023 for alum and p = 0.008 for no adjuvant, Kruskall - Wallis); also, geometric mean
titers were higher for the groups given
lower vaccine dosages.
Similarly, it is provocative, albeit speculative, to note in the
lower dose of the vaccine seemed to yield a stronger response than the higher dose on several outcomes: Ab
titer, IGA, and potentially even adverse reactions.
CONCLUSIONS: Approximately 4.6 years after immunization with AN1792, patients defined as responders in the phase 2a study maintained
low but detectable, sustained anti-AN1792 antibody
titers and demonstrated significantly reduced functional decline compared with placebo - treated patients.
Low anti-Abeta
titers were detected in CSF.
Antibody
titers of positive control anti-sera and reactivity of pre-immune sera to polytropic MuLV - infected (upper panel) and uninfected (
lower panel) HeLa cell crude cell lysates in WB testing.
So, even if a
titer test shows your pet has a
low number of antibodies, or even no antibodies, that doesn't necessarily mean your pet is unprotected.
The combination of high
titer and
low passage gives VANGUARD Plus CPV the immunogenic properties capable of stimulating active immunity in the presence of maternal antibodies.
For
low - burden suspects, commercial laboratory - based microwell
titer tests are the most sensitive.
This test differentiates those dogs whose infections need to be treated from those whose
titers are so
low that they are clinically insignificant.
In some cases, the pet will have a
low or negative
titer, yet have more severe symptoms than expected.
The problem arises when a highly desired breeding cat is positive at
low corona antibody
titer levels (1:10 - 1:25).
If you're vaccinating a puppy, or a young dog with
low antibody
titers, ask your vet to use a monovalent vaccine (meaning the vial contains only one vaccine).
I currently prefer multiple
low - dilution antibody
titer tests over RT - PCR tests for identifying non-carrier cats.
If the
titer is
low, then the vaccine can be appropriately given.
If the
titer is adequate and the likelihood a dog will be exposed to these organisms is
low, then the decision to hold off on the vaccination can be made under the guidance of the veterinarian providing care.
The use of a high
titer low passage DHPP vaccine will assist a puppy's immune system in developing protection at a younger age then DHPP vaccines which are not high
titer low passage.
If vaccination
titers are
low, then booster vaccinations may be considered, depending on the lifestyle, health, and age of your pet.
One Year Later (approximately 16 months old):
Titer preferred, or repeat DHPP vaccination One Year Later (approximately 28 months old): Perform titer; vaccinate only if protective levels are low, otherwise repeat titer in 1 - 3 y
Titer preferred, or repeat DHPP vaccination One Year Later (approximately 28 months old): Perform
titer; vaccinate only if protective levels are low, otherwise repeat titer in 1 - 3 y
titer; vaccinate only if protective levels are
low, otherwise repeat
titer in 1 - 3 y
titer in 1 - 3 years.
Many vets and pet owners are fond of using
titers to determine whether a dog requires revaccination with the understanding that a
low titre equals
low immunity.
For example, a positive rabies
titer of 1:2 is very
low and would not be proof of immunity to rabies.
While
low or borderline
titers are open to interpretation, most experts agree that a high
titer indicates good protection from the disease.
A
low or absent
titer, therefore, does not mean the body is unprotected.