In overweight or obese subjects, IER (60 - 85 % ER / alternate days) have been shown to produce an average weight loss of between -5 and -8 % body - weight in studies of four to 12 weeks duration with the degree of weight - loss seemingly correlated to the length of the intervention.37, 38, 40, 45 - 47, 49 - 52 Weight - loss is accompanied by reductions in whole - body adiposity 37, 38, 40, 45 - 47, 49 - 52, waist circumference39, 40, 43, 45 and favourable shifts in adipokine expression encompassing
lowered circulating levels of TNF - a 37, IL - 6 37, resistin 39, 49 and augmented adiponectin expression 39, consistent with favourable modulations in adipose function.
Evidence is accumulating that DHEA may be effective as a treatment for the immunological abnormalities that arise in subjects with
low circulating levels of this hormone, including the impaired immune response of older individuals and immune dysregulation in patients with chronic autoimmune disease.93
The results demonstrated that men with
low circulating levels of testosterone had an 88 % increased risk of mortality.
I did a search looking a studies investigating IGF - 1 and the intake of animal v plant protein and there is clear indications that a plant - based diet is associated with
lower circulating levels of total IGF - 1, discerning if the animal protein came directly from the animal or was in supplemental form was not attempted.
This magical fruit also is found to
lower circulating levels of the angiotensin hormone that can help blood vessels to relax.
Dogs that have hypothyroidism, thyroid gland tumors (thymomas),
low circulating levels of platelets or Addison's disease (hypoadrenocorticism) also are more likely to develop acquired myasthenia gravis as they mature.
Not exact matches
It is important to understand that breastfed babies may have
low iron stores, by design, but the
level of available iron actually
circulating in their blood (hemoglobin
level) is the measure that counts at this age.
The researchers found that treating the mice with a drug that
lowers blood sugar
levels not only reduced the numbers of
circulating monocytes and neutrophils but also allowed plaques to normally heal after blood cholesterol was reduced.
If
circulating levels of D are
low, macrophages can't activate the vitamin D to initiate this response.
The cases leave public health authorities in the U.S. and elsewhere wondering if a new swine - origin flu virus is
circulating at
low levels among humans — and what needs to be done if that is indeed happening.
«Partial sleep deprivation may increase the risk of overeating in the evening due to
low circulating leptin
levels and additional time spent awake,» the researchers noted, adding that «evening and late - night hours are when overeating of less - healthful foods is most likely to occur.»
«Despite having
low levels of
circulating testosterone, very few subjects reported symptoms consistent with testosterone deficiency or excess,» Page said.
Disrupting nerve fibers to the adrenal glands by high -
level but not
low -
level thoracic spinal cord transection resulted in almost complete suppression of
circulating norepinephrine
levels and profound stimulation of systemic corticosterone
levels.
The study, published in the journal BioMed Central Obesity, looked at the effects of three
levels of vitamin D supplementation in 70 overweight - to - obese blacks under age 50 living in the Southeastern United States who appeared healthy, although their
circulating level of vitamin D was considered
low.
In addition to effects on the brain, Brody's research with the SAAF participants has found they have
lower levels of stress hormones
circulating in their bodies, they have
lower levels of inflammation, and they are less likely to show biological markers of premature aging.
They found that
low circulating vitamin D
levels in blood were associated with increased mortality risks from cardiovascular disease, cancer, and other causes.
The problem is that
levels of prions
circulating in blood plasma are extremely
low, so any test would need to be exquisitely sensitive.
Physicians try to keep the
lowest level, the trough, from falling below 1 % of the amount a non-haemophiliac person has
circulating in their blood, enough to prevent spontaneous bleeding.
Although irisin
circulates at
low levels (nanograms), this range is comparable to that observed for other important biological hormones such as insulin.
In this respect, it is known that the
circulating levels of myostatin protein in humans are considerably
lower than in mice [14], [21], raising the possibility that the balance of the relative roles played by myostatin and by these other regulators may have shifted further away from myostatin in humans compared to mice.
As noted previously (12, 16), SED db / db mice in the current study had
lower circulating osteocalcin
levels than SED WT mice.
Instead, it was an Asian strain of chik that had been
circulating at
low levels for decades, producing its own mutant swarms.
Telomere length predicts both cellular health and disease in rodent models and humans.8 Shorter telomeres predict onset of cardiometabolic diseases of aging.9 Chronic stress is associated with higher inflammation, shorter telomeres, and
lower activity
levels of telomerase, the cellular enzyme that elongates telomeric DNA.10, 11 Levels of amyloid beta (Aβ) proteins circulating in the blood appear to be stress - related in rodent models12 and may be affected by stress reduction, and greater Aβ42 / Aβ40 ratios are associated with lower risk of demen
levels of telomerase, the cellular enzyme that elongates telomeric DNA.10, 11
Levels of amyloid beta (Aβ) proteins circulating in the blood appear to be stress - related in rodent models12 and may be affected by stress reduction, and greater Aβ42 / Aβ40 ratios are associated with lower risk of demen
Levels of amyloid beta (Aβ) proteins
circulating in the blood appear to be stress - related in rodent models12 and may be affected by stress reduction, and greater Aβ42 / Aβ40 ratios are associated with
lower risk of dementia.13
In everyone, stem cells that reside primarily in the bone marrow, leave and
circulate in the blood stream at very
low levels.
It has been proven that women eating higher amounts of fiber have
lower levels of
circulating estrogen.
Because the brain is unable to
lower circulating blood sugar
levels these
levels remain high.
However, it has been proven that women eating higher amounts of fiber have
lower levels of
circulating estrogen, so it's worth a try!
However, this test can often times be misleading, as
levels of
circulating hormones may fluctuate at different times, such as in Hashimoto's, where the person affected may fluctuate between highs and
lows.
Well, if that's the case, do vegetarians have
lower levels of flame - retardant chemical pollutants
circulating in their bloodstreams?
Sex hormone - binding globulin (SHBG):
Levels of SHBG also increase with age, which makes the bioavailability of testosterone
circulating in the bloodstream
lower.
Irritability during menopause is most often caused by hormonal changes, whereby
low levels of
circulating estrogen have an adverse effect on the neurotransmitters in the brain that are responsible for regulating mood.
This causes the body to convert more cholesterol into bile acids, which ultimately has the effect of
lowering circulating cholesterol
levels.
Low levels of spexin are linked to pediatric obesity5Kumar, S., et al. «Decreased
circulating levels of spexin in obese children.»
Patients with advanced AD show higher plasma but
lower CSF insulin concentrations than healthy controls.40 Clearly, then, the
lower concentration of insulin in the brain is not a result of reduced
circulating levels in the blood.
Overall, our human and animal studies indicate that a
low protein diet during middle age is likely to be beneficial for the prevention of cancer, overall mortality, and possibly diabetes through a process that may involve, at least in part, regulation of
circulating IGF - 1 and possibly insulin
levels.
Studies have shown that women on a high - fiber diet have
lower levels of
circulating estrogen, meaning less estrogen stimulation of breast tissue, for example, which reduces the risk of breast cancer.
It appears that as well as the state of ketosis and the neuroprotective role that ketone bodies generally display, the
lower glucose
levels, as well as other
circulating fatty acids i.e. PUFAs also contribute to the anti-seizure effect (8)
Studies have shown that women on a high - fiber diet have
lower levels of
circulating estrogen.
Higher
Circulating hsCRP
levels are associated with
lower bone mineral density in healthy pre - and postmenopausal women: evidence for a link between systemic inflammation and osteoporosis.
Both high estrogen
levels and
low progesterone increase
levels of «thyroid binding globulin», which means that
circulating thyroid hormones decrease and hypothyroid symptoms appear.
For decades, it's been known that starvation and very -
low - calorie diets decrease the
level of
circulating thyroid hormones in the bloodstream (3, 4).
This is presumably why those who eat less meat, egg white, or dairy proteins have significantly
lower levels circulating within their bodies within weeks of making the dietary switch.
This opens a window in the cell that allows glucose to flow into the cell through a concentration gradient where it can be metabolized for energy while
lowering circulating blood sugar to stable
levels (9).
One study found women with PCOS who take vitamin D supplements may have
lower fasting blood sugar
levels and
lower circulating insulin (remember: extra insulin in circulation causes a lot of the insulin resistance symptoms).
High
levels of insulin will
lower circulating IGFBP3 delaying apoptosis of keratinocytes that line the follicle, leading to more flaky cells to clog up your pores.
Interestingly, the
low - grade inflammation correlates with
circulating levels of a plasma endotoxin known as lipopolysaccharide (LPS).
They may increase the rate at which your body metabolizes and gets rid of the levothyroxine, again resulting in
lower circulating blood
levels of thyroid medication in your bloodstream
Part of the mechanism is by androgenic interference with the estrogen receptor (ER) and
lowering circulating estrogen
levels by competitively inhibiting the aromatase enzyme.
As expected, the
lower - carbohydrate diet resulted in significantly greater
levels of
circulating ketones (∼ 3 mmol / l), which was strongly associated with a
lower hepatic glucose output.
In a longer study35 obese T2D individuals were prescribed a well - formulated ketogenic diet for 56 weeks, and significant improvements in both weight loss and metabolic parameters were seen at 12 weeks and continued throughout the 56 weeks as evidenced by improvements in fasting
circulating levels of glucose (− 51 %), total cholesterol (− 29 %), high - density lipoprotein — cholesterol (63 %),
low - density lipoprotein — cholesterol (− 33 %) and triglycerides (− 41 %).