Comparison of smoking and non-smoking
lung cancer patients finds differences in clinical signs and survival rates.
Not exact matches
Urbanic said the overall
findings of the study suggest that there are some
patients with recurrent
lung cancers who can be treated with another definitive course of radiation therapy and still have a chance at a cure.
Findings were presented at the WCLC are based on the updated results of 12
lung cancer patients enrolled in the clinical trial with pembro and irinotecan or gemcitabine with or without vinorelbine or docetaxel.
Key
findings in this study show that 5 - year survival for older
lung cancer surgery
patients is favorable; surgeons will be able to better individualize care for older
lung cancer patients based on newly and uniquely linked data, and the prevalence of
lung cancer is expected to increase as the population continues to age.
«Our
findings suggest that this new drug combination would also help
patients with this type of aggressive breast
cancer as well as other
cancers, such as
lung, prostate and ovarian
cancers,» Dr. Rassool says.
Recent
findings suggest a novel positron emission tomography (PET) imaging approach determining epidermal growth factor receptor (EGFR) mutation status for improved
lung cancer patient management.
They
found out that TiY is capable of distinguishing TICs from non-TICs in various human
lung cancer cell lines and
patient - derived
lung tumors.
The team
found that
patients with breast, gastric or
lung cancers survived longer when they had higher levels of Bmal1 protein.
Epidermal growth factor receptor (EGFR) mutations
found in the circulating free tumor DNA (ctDNA) from the plasma of advanced non-small cell
lung cancer (NSCLC)
patients correlates well with the EGFR mutations from
patient - matched tumor tissue DNA.
In the malignant tissue, they
found up to 1500 genes with mutations — a level higher than has been
found for either
lung cancer in smokers or skin
cancer in
patients with heavy exposure to ultraviolet radiation.
An international study involving Manchester researchers has
found that for previously untreated
lung cancer patients with a particular genetic change, a new targeted therapy is better than standard chemotherapy.
Commenting on the
findings, Prof Robert Pirker, programme director for
lung cancer at the Vienna General Hospital in Vienna, Austria, not involved in the study, said: «This subgroup analysis shows that the effect of necitumumab was slightly greater in
patients with EGFR expressing tumours than it was in the entire SQUIRE population.
The study, called «Molecular Determinants of Drug - Specific Sensitivity for Epidermal Growth Factor Receptor (EGFR) Exon 19 and 20 Mutants in Non-Small Cell
Lung Cancer,» and published online in the journal Oncotarget, demonstrates how computer modeling of EGFR mutations found in lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat patie
Lung Cancer,» and published online in the journal Oncotarget, demonstrates how computer modeling of EGFR mutations found in lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat pat
Cancer,» and published online in the journal Oncotarget, demonstrates how computer modeling of EGFR mutations
found in
lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat patie
lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat pat
cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat
patients.
A recent study in Manchester has
found that a procedure to take tissue samples from
lung cancer patients can be used safely in the elderly — allowing doctors to make a more accurate diagnosis and to choose appropriate treatment.
Islam and colleagues
found that among
patients with localized
lung cancer, those with one comorbidity had a 30 percent higher risk of mortality compared with those who had no comorbidity.
Their initial experiments
found increased bone activity in two mouse models of a common form of
lung cancer and in 70
lung cancer patients, even in absence of bone metastasis.
An analysis of
lung cancer incidence and screening
found a decline in the proportion of
patients with
lung cancer meeting high - risk screening criteria, suggesting that an increasing number of
patients with
lung cancer would not have been candidates for screening, according to a study in the February 24 issue of JAMA.
The researchers
found there was a decline in the relative proportion of
patients with
lung cancer meeting the USPSTF criteria overall, from 57 percent in 1984 - 1990 to 43 percent in 2005 - 2011.
The authors
found that most
lung cancer patients (regardless of stage) want physical activity advice directly from a physician at a
cancer center before
cancer treatment and exercise guidance may increase compliance with a dedicated program.
On the streets of the
cancer villages and in the
lungs of the meso ¬ thelioma
patients, Baris, Pooley and their collaborators
found microscopic bits of erionite, which has fibrous qualities like those of asbestos.
Clinical trials
found that it is safe to regularly infuse brain and
lung cancer patients with 800 — 1000 times the daily recommended amount of vitamin C as a potential strategy to improve outcomes of standard
cancer treatments.
They
found that high biglycan expression was associated with poor prognosis in
patients with breast,
lung and colorectal
cancer.
«We
found tumor regression in almost half of these early stage
lung cancer patients.
The
findings may give hope to the nearly 30 percent of
patients with non-small cell
lung cancer (NSCLC) whose tumors lack LKB1 (also called STK11).
DENVER — Leptomeningeal metastases (LM), a devastating complication and predictor of poor survival in
lung cancer patients, was
found to be more prevalent in non-small cell
lung cancer (NSCLC)
patients with epidermal growth factor receptor (EGFR) mutations.
We're discovering new genetic alterations driving
lung cancer, new drugs to target these alterations, and are refining our use of tests to find these alterations in individual patients,» says Dara Aisner, MD, PhD, investigator at the University of Colorado Cancer Center, molecular pathologist at CU School of Medicine Department of Pathology, and one of the panel ex
cancer, new drugs to target these alterations, and are refining our use of tests to
find these alterations in individual
patients,» says Dara Aisner, MD, PhD, investigator at the University of Colorado
Cancer Center, molecular pathologist at CU School of Medicine Department of Pathology, and one of the panel ex
Cancer Center, molecular pathologist at CU School of Medicine Department of Pathology, and one of the panel experts.
Researchers have
found that treating
patients who have early stage non-small cell
lung cancer with a type of radiotherapy called stereotactic body radiation therapy is associated with a small but increased risk of death from causes other than
cancer.
Now, on Nov. 5, a news story likened those
findings to the results of a large trial by the National
Cancer Institute, which showed that CT scans reduced mortality rates among the highest - risk lung cancer patients by 20 pe
Cancer Institute, which showed that CT scans reduced mortality rates among the highest - risk
lung cancer patients by 20 pe
cancer patients by 20 percent.
Among the most exciting
findings of these studies is that a significant proportion of
patients with non-small cell
lung cancer (NSCLC) respond dramatically to anti-PD-1 treatment.
Assuming that the
findings of the review reflected a causal relation between smoking cessation and risk of all cause mortality, we further investigated the data by constructing life tables for a hypothetical group of 100
patients aged 65 years with early stage
lung cancer to estimate how many deaths would be prevented by smoking cessation within the non-small cell
lung cancer and small cell
lung cancer populations during five years.
But techniques aren't yet sensitive enough to be able to monitor
patients with «solid» tumours
found in
lung and bowel
cancer.
Whitehead Institute researchers have
found that an ancient, highly conserved cell survival factor drives expression of a specific set of genes that is strongly associated with metastasis and death in
patients with breast, colon, and
lung cancers.
The risk of cardiovascular related illness and death is known to decrease after smoking cessation in
patients with coronary heart disease, 40 reducing dramatically over the first three years, 41 but reducing the risk of developing
lung cancer after smoking cessation generally takes longer.9 41 This review has
found evidence that after
lung cancer has been diagnosed, reductions in risk of developing a second primary or recurrence were associated with quitting within seven years, suggesting that, even at this stage, the prognostic outlook can be improved by smoking cessation.
DNA Detectives
Find Genetic Markers for
Lung Cancers Most Likely to Recur Researchers at the Johns Hopkins Kimmel Cancer Center uncovered clearly recognizable genetic alterations in tumors and tissue removed from patients with early - stage lung cancers that look like good predictors of which of these cancers are more likely to re
Lung Cancers Most Likely to Recur Researchers at the Johns Hopkins Kimmel Cancer Center uncovered clearly recognizable genetic alterations in tumors and tissue removed from patients with early - stage lung cancers that look like good predictors of which of these cancers are more likely to
Cancers Most Likely to Recur Researchers at the Johns Hopkins Kimmel
Cancer Center uncovered clearly recognizable genetic alterations in tumors and tissue removed from
patients with early - stage
lung cancers that look like good predictors of which of these cancers are more likely to re
lung cancers that look like good predictors of which of these cancers are more likely to
cancers that look like good predictors of which of these
cancers are more likely to
cancers are more likely to recur.
Epidermal growth factor receptor, also called EGFR, is a biomarker
found in certain
patients with
lung cancer.
Vascular endothelial growth factor receptor, also called VEGFR, is a biomarker
found in certain
patients with
lung cancer.
A K - ras mutation called KRAS 1 is a biomarker
found in certain
patients with
lung cancer.
Mary O'Brien, an oncologist at Royal Marsden Hospital in London, first stumbled upon these
findings while inoculating
lung cancer patients with a strain of M. vaccae (pronounced «emm vah - kay») to see if their symptoms improved.
Clinical trials have
found that regularly infusing brain and
lung cancer patients with 800 to 1000 times the daily recommended amount of vitamin C...
These
findings are consistent with previous research, in which caregiving burden among spouses of
patients with
lung cancer was related to 3 - and 6 - month follow - up distress in spouses.