Sentences with phrase «lung growth with»

«Children who had low lung function at the start of the trial followed a series of predicted growth patterns: most had reduced lung growth with time and a significant number would go on to meet the criteria for COPD.»

Not exact matches

The AAP Committee on Environmental Health has identified these problems with secondhand smoke exposure: decreased lung growth, decreased lung function, and increased frequency of lower respiratory tract infections and respiratory symptoms.

Geoff Oxnard, an assistant professor of medicine at Dana - Farber Cancer Institute and Harvard Medical School in Boston and one of Paweletz's collaborators, remarks that «I had a hospitalized patient last week, she's sick with metastatic lung cancer, and she's exactly the kind of patient who might have an [epithelial growth factor receptor (EGFR)-RSB- mutation, but I simply didn't have enough tissue to ask those questions yet.»

To their surprise, they found that these Th17 - deficient mice experienced far more aggressive cancer growth than normal mice — with the cancer completely smothering the lungs within 16 days.

The trial also recorded fewer cases of lung cancer in those on the treatment, consistent with basic research findings hinting that the same inflammatory pathway may initiate or spur tumor growth.

A drug approved by the Food and Drug Administration (FDA) for melanoma in combination with a common cholesterol - lowering drug may show promise in controlling cancer growth in patients with non-small cell lung cancer (NSCLC), according to new research from the Icahn School of Medicine at Mount Sinai.

Multiplexed genetic screening for epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) gene rearrangements and subsequent biomarker - guided treatment is cost - effective compared with standard chemotherapy treatment without any molecular testing in the metastatic non-small cell lung cancer (NSCLC) setting in the United States.

Among patients with advanced non-small cell lung cancer without a mutation of a certain gene (EGFR), conventional chemotherapy, compared with treatment using epidermal growth factor receptor tyrosine kinase inhibitors, was associated with improvement in survival without progression of the cancer, but not with overall survival, according to a study in the April 9 issue of JAMA.

Patients with epidermal growth factor receptor (EGFR) expressing advanced squamous non-small-cell lung cancer benefit most from necitumumab added to gemcitabine and cisplatin chemotherapy, according to a subgroup analysis from the SQUIRE trial presented today at the European Lung Cancer Conference (ELCC) 2016 in Geneva, Switzerllung cancer benefit most from necitumumab added to gemcitabine and cisplatin chemotherapy, according to a subgroup analysis from the SQUIRE trial presented today at the European Lung Cancer Conference (ELCC) 2016 in Geneva, SwitzerlLung Cancer Conference (ELCC) 2016 in Geneva, Switzerland.

Epidermal growth factor receptor (EGFR) mutations found in the circulating free tumor DNA (ctDNA) from the plasma of advanced non-small cell lung cancer (NSCLC) patients correlates well with the EGFR mutations from patient - matched tumor tissue DNA.

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are the preferred treatment option for patients with advanced non-small cell lung cancer (NSCLC) who have mutations in the EGFR gene.

With these annual recordings, the researchers were able to characterize the patterns of growth in asthmatics» lung function.

The cells exhibited many functions associated with tumor progression; their presence within mouse tumors substantially accelerated cancer growth, and in human lung tumors, a SiglecFhigh neutrophil signature was associated with poor patient survival.

The researchers next showed that the Smurf1 gene controls M. tuberculosis growth in human macrophages and that the Smurf1 protein was found in association with bacteria in the lungs of patients with tuberculosis infections.

«BMI1 plays a substantial role in many solid tumors, including one of the most aggressive models of lung cancer, and its expression is linked with tumor growth, invasion, metastasis, prognosis and recurrence,» Levantini said.

«The information we have gained about the dynamic changes in ECM composition and its interactions with various secreted growth factor proteins enables us to develop new hypotheses for the activation of stem cells in the lung,» explains Dr. Herbert Schiller, first author of the study.

Injections of iPSC - EPCs did not however have significant effect on tumor growth or on overall survival, but transducing cells with a baculovirus expressing CD40L, a member of the TNF gene family which can induce apoptosis [6, 7], and injection into the breast cancer lung metastasis, increased levels of pro-apoptotic cytokines in lung tissues, indicating the induction of apoptosis by CD40L carried by the EPCs (See figure).

Children with thoracic insufficiency syndrome often experience impaired breathing or lung growth.

Together with oncologist William Pao, she uncovered differences in the growth dynamics of non-small cell lung cancer cells that are either resistant or susceptible to the targeted drug Tarceva.

DENVER — Leptomeningeal metastases (LM), a devastating complication and predictor of poor survival in lung cancer patients, was found to be more prevalent in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations.

When they blocked IKK2 activity in the mice with lung cancer, the mice had smaller tumors and lived longer, suggesting that the enzyme is necessary for NF - KB to stimulate tumor growth.

Binding of JSRV sheep lung cells might interfere with the receptor's normal role in regulating cell proliferation, causing unregulated growth.

The «early low, accelerated growth, normal decline» path also suggested a somewhat surprising pathway, where some children with low lung function in childhood still had an opportunity to grow out of it.

early low, accelerated growth, normal decline (new)-- those with low lung function in early childhood followed by a catch - up growth during adolescence and remain normal in adulthood;

Along the same lines, in non-small cell lung cancer (NSCLC), acquired resistance to Gefitinib / Erlotinib kinase inhibitors has also been associated with a secondary mutation of the gatekeeper Thr790 residue of the epidermal growth factor receptor (EGFR).

Our extensive leadership in research offers our patients access to the latest clinical trials, and we are often one of only a few centers offering access to certain therapies, such as the lung - growth trials for patients with congenital diaphragmatic hernia.

Epidermal growth factor receptor, also called EGFR, is a biomarker found in certain patients with lung cancer.

Vascular endothelial growth factor receptor, also called VEGFR, is a biomarker found in certain patients with lung cancer.

With saffron, prevention of rapid cancer cell growth has been observed in cases of pancreatic, lung, colon and breast cancer growth.

Eating foods high in this fat - soluble phytochemical (meaning that in order for our bodies to uptake it, it does need to be eaten with a fat) is correlated with a reduced risk of various cancers, including prostate, breast, and lung cancers due to its ability to bind to and deactivate insulin - like growth factors (IGF)-- these are the cells that often become cancer cells.

Over the past several years, studies in cell cultures and animals have found that metformin appears to slow or stop the growth of a wide range of cancer cells, including those associated with breast, prostate, lung, and endometrial cancer.

A German research report revealed that dogs are able to find early - stage lung cancer, and countless reports have revealed that canines can sniff a cancerous growth in humans long before the growth is visible with the naked human eye.

Dogs with metastatic lung cancers generally have several tumors in the lungs, not just a single growth.

As dogs age, there is an increased chance of growths, and disease occurring, and he may have a problem with his nasal passages or lungs.

This includes weight monitoring, oral exam, ocular exam, ear exam, listening to the heart and lungs with a stethoscope, abdominal palpation, and examination of the skin and fur, looking for any lumps or growths.