"Lung injury" refers to any harm or damage that occurs to the lungs. It can be caused by various factors such as infections, diseases, or physical injuries.
Full definition
He will measure immune system markers from each group, and compare their outcomes,
including lung injury, organ failure and death.
Studies show 40 - 60 ppm
produces lung injury; 430 ppm usually causes death in 30 minutes, and 1,000 ppm is fatal within a few minutes.
Previous scientific studies have revealed that acute
lung injury caused by the influenza virus is the result of an immune reaction mediated by a protein called Toll - like receptor 4 (TLR4).
Calcitonin gene - related peptide (CGRP) has been shown to improve survival of lung epithelial cells and reduce
hyperoxic lung injury in rats.
Further, in laboratory mice, the team found that by deleting this substance, they could produce the type of scarring found in pulmonary fibrosis
after lung injury.
It also reduces the chances that the newborn will
develop lung injury or abnormal lung development, a condition called bronchopulmonary dysplasia, which can lead to higher rates of breathing problems later in life.
The scientists conclude that in mice «well - timed treatment with rIL - 27
improved lung injury and accelerated recovery without affecting viral clearance» and continue «these data demonstrate that IL - 27 has a unique role in controlling immunopathology without impacting on host defense, and might therefore represent a promising candidate for immunomodulatory therapy of viral pneumonia.»
«These findings could motivate future research to find other treatments for this group with
ongoing lung injury.»
In AE,
widespread lung injury is superimposed on the pulmonary fibrosis, which frequently occurs before patients die.
The authors implicate it as the «master regulator» of what appears to be a tragically errant repair response to the
mysterious lung injuries that give rise to the disease.
These findings suggest that targeting NFAT activity might be a useful way to
ameliorate lung injury in severe streptococcal infections.
Angela Panoskaltsis - Mortari, who
studies lung injury and repair at the University of Minnesota, Minneapolis, agrees.
By triggering a process called autophagy — in which cells literally engulf their own insides — researchers from Drexel University and Yale University were able to
decrease lung injury in mice that were exposed to high concentrations of oxygen.
The worst chlorine gas accident in the country occurred in 2005, when 18 freight train cars derailed and released 120,000 pounds of chlorine gas in the mill town of Graniteville, S.C. Nine people were killed and at least 1,400 people were exposed, resulting in more than 550 people treated at hospitals, including some with
serious lung injuries.
Researchers at Johns Hopkins University checked in with survivors of a
lifethreatening lung injury for two years after they were discharged from the ICU.
Naringenin ameliorates LPS - induced acute
lung injury through its anti-oxidative and anti-inflammatory activity and by inhibition of the PI3K / AKT pathway.
Recruitment of circulatory fibrocytes and bone marrow derived progenitor cells
during lung injury is guided by the SDF - 1 / CXCR4 axis promoting the pathogenesis of pulmonary fibrosis.
The HARP study showed that 80 mg of simvastatin administered acutely to patients with acute
lung injury showed significant improvements in organ failure scores, suggesting that statins modulate the systemic inflammation after only a short duration of treatment [17].
Serve as local counsel in approximately 600 cases for an international flavors company in defense of claims
alleging lung injury due to exposure to butter flavoring.
Manage Project tilted «
Modulating lung injury with Stem cells», conduct various in vivo and in vitro experimentation related to project.
Highly pathogenic (dangerous) influenza strains elicit a strong immune response which can lead to uncontrolled inflammation in the lung and potentially
fatal lung injury.
Calcitonin Gene - Related Peptide Enhances the Expression of Signaling Molecules of the Wnt 7b / Beta - Catenin Pathway in Rat Type II Alveolar Epithelial Cells Under Hyperoxia
Hyperoxic lung injury is characterized by epithelial cell death and leukocyte infiltration / inflammation in the lung.
To find out whether increasing cell self - destruction in the lungs could actually decrease cell death — and ultimately
prevent lung injury — Bhandari and his research team targeted a regulator protein called RPTOR, which when inhibited, is responsible for inducing autophagy.
«Adding fuel helps fighting the fire: Cortisone affects acute
lung injury via pro-inflammatory signalling pathways.»
In the aftermath of 9/11, New York City fire department rescue and recovery workers exposed to the caustic dust at the site experienced high rates
of lung injury and excessive loss of lung function.
They discovered that in the young, more immune cells called monocytes were recruited to the lungs, and that the gene expression profiles of these cells had more inflammatory features, causing greater inflammation and more
severe lung injury.
NYSCF — Druckenmiller Fellow Zhongwei Cao, PhD, conducts research that may yield breakthrough treatments
for lung injury.
The researchers said that caffeine appeared to improve long - term breathing by
reducing lung injury and abnormal development during the newborn period, «rather than the caffeine molecule having any direct effect on the lung itself.»
Kenneth R. Cooke, M.D. University of Michigan Medical School
Acute lung injury after SCT: from laboratory insights to novel strategies for diagnosis and treatment
Informed by such studies, the military has since developed bulletproof vests that have dramatically decreased the number of blast - induced
lung injuries in recent years.
While this process causes
some lung injury, most of the symptoms of the flu are actually caused by the immune response to the virus.
He showed me the scars on the back of his enormously strong legs and told me about his brain, stomach, and
lung injuries.
One flavonoid in lemongrass called luteolin has such strong anti-inflammatory abilities that it may be able to treat some symptoms of multiple sclerosis, as well as lung infections or acute
lung injury.
Theo is still recovering from
the lung injury that he sustained on international duty with England and needs some game time to make sure he's at full fitness.
Acute
lung injury develops as a result of direct or indirect trauma to the lungs.
What physicians know as «acute
lung injury» (ALI) otherwise leads to death by suffocation without immediate treatment.
This acute
lung injury (ALI) is treated through artificial respiration and anti-inflammatory cortisone.
Phrases with «lung injury»