2 — photomicrograph of H&E stained
lung tissue showing a severe diffuse necrotizing bronchopneumonia characterized by the presence of hemorrhage and intranuclear inclusions (arrows).
They exposed rats to it, and
their lung tissue showed telltale signs of stress that's a common precursor to cardiovascular problems.
Not exact matches
In lab experiments using
tissue samples cultured from cystic fibrosis patients, scientists at the UNC School of Medicine and the UNC Marsico
Lung Institute have
shown that a new CF drug counteracts the intended beneficial molecular effect of another CF drug.
Interdisciplinary research at the University of Pennsylvania is
showing how cells interact over long distances within fibrous
tissue, like that associated with many diseases of the liver,
lungs and other organs.
The experiments, including studies conducted in a bioengineered 3 - D model of
lung tissue seeded with relevant cells,
showed that CHI3L1 regulates a pathway that recruits cells such as macrophages and fibroblasts that produce the scarring, or fibrosis.
The researchers
showed that this technique works for many types of
tissues, including brain, pancreas,
lung, and spleen.
This
shows promise for breast cancer patients as diagnosing and treating the breast cancer at early stages means there is a greater chance of preventing cancer cells spreading to other
tissues, such as the
lungs, brain and bone.
Previous research, including pioneering work at MD Anderson by this study's senior author Ignacio Wistuba, M.D., and others, has
shown normal - appearing
tissue close to
lung premalignant and cancer lesions may have tumor - associated molecular abnormalities.
According to their report, released in October, the subjects
showed unusual changes in their
lung tissue at roughly eight times the rate seen in a study of similarly aged transportation workers, although these could have had many causes.
The
tissue specimens
showed that although there were intestinal lesions in most cases, there were also lesions in the lymph nodes that drain the
lungs, and in the
tissue between the
lungs called the mediastinum.
Now an international team of researchers led by the
lung researcher Marianne Geiser from the Institute of Anatomy at the University of Bern and the aerosol researcher Josef Dommen from the Paul Scherrer Institute PSI has
shown that secondary particles from gasoline combustion in Euro 5 engines directly damage
lung tissue as well as weaken its defense functions.
She
showed that patients with emphysema had deterioration of elastin, which destroyed their
lung tissue.
Different types of tumors
show a preference for specific organs and
tissues; circulating breast cancer cells, for example, are likely to take root in bones,
lungs, and the brain.
Together with researchers of the Research Center Borstel, the
Lung Clinic Grosshansdorf, the Technische Universität Braunschweig, and the Ostfalia University of Applied Science, Jänsch
showed that the treatment of
tissue with the HOPE technique combines all advantages of standard fixation strategies.
But in earlier work Drs. Summer and Romero have
shown that when
lung tissue is injured — by things like viral infection, particulate inhalation, or other insults —
lung cells eventually stop producing lipids in order to conserve energy for other cellular repairs.
An autopsy of one victim of H5N1
showed that most of the virus had grown deep in the
lung tissue.
A new study
shows that restoring the lipids that help keep
lung tissue flexible and inflated can help slow disease progression in laboratory models of pulmonary fibrosis.
Two alpha globin genes, HBA1 and HBA2, involved in the transport of oxygen from the
lung to the peripheral
tissues,
show an increased expression in several
tissues but not in blood, where they are the most expressed genes (Fig. 2d).
â $ œWe have solved a major obstacle of using anti-miRNA as a therapeutic by being able to do a targeted delivery to only inflamed endothelial cells while all other
tissues examined, including liver,
lung, kidney, blood cells, spleen, etc
showed no detectable side - effects, â $ Jo says.
ORs are also expressed in non-olfactory
tissues, including the kidney, heart,
lung, and testes [9], [10], where they have been
shown to work as chemoreceptors in human sperm chemotaxis [11], [12].
Clinical and laboratory studies have
shown that NY - ESO - 1 is present in many different cancers — including melanoma,
lung, breast, and ovarian cancers — and not in most healthy
tissue.
A rapidly growing number of published studies have
shown that M. oleifera leaves possess a wide range of additional biological activities including antioxidant,
tissue protective (liver, kidneys, heart, testes, and
lungs), analgesic (pain relieving), antiulcer, antihypertensive, radioprotective, and immunomodulatory actions.
Studies in animals and humans have
shown that dietary glutathione increases blood levels of glutathione, but one study in mice suggested that under ordinary conditions, dietary glutathione can not boost its own concentration in other
tissues except in the
lung, where large amounts of glutathione are needed to maintain the fluidity of mucus.
The chest radiographs may
show an enlarged heart and / or fluid in the
lung tissue or chest cavity.
Thoracic radiography is useful to evaluate pulmonary (
lung)
tissue and vessels, and may
show evidence of fluid accumulation in the
lungs (pulmonary edema) or around the
lungs (pleural effusion).