But new research at Washington University School of Medicine in St. Louis suggests that broadly dampening the immune response, long considered crucial to transplant success, may encourage
lung transplant rejection.
Not exact matches
Whereas most conventional scientists focus on a single system or disease, Butte earned tenure recently with a dossier of advances in diabetes, obesity, and
transplant rejection, and the discovery of new drugs for
lung cancer and other diseases.
«Reading small
lung transplant biopsies with a microscope is challenging — much more so than other transplantable organs — and that makes diagnosing
rejection that much more difficult and prone to error,» explained Kieran Halloran, assistant professor of medicine in the U of A's Faculty of Medicine & Dentistry.
Sirolimus sometimes is given to
lung transplant patients to prevent
rejection.
Her group wanted to make
lung tissue from the body's own cells, to prevent
rejection when
transplanted.
Without these cells, the immune system recognizes a newly
transplanted lung as harmful and mounts an attack that eventually can lead to
rejection of the organ.
But in
lung transplants, this strategy may contribute to organ
rejection.»
«We think this approach to preventing organ
rejection has the potential to offer significant benefits to those in need of heart,
lung, liver and bone marrow
transplants.»