Not exact matches
«We
also confirmed that human
patients with a missing or malfunctioning DNASE1L3 gene had an abundance of circulating DNA and developed antibodies to it, and that such antibodies were
also present in most forms of
lupus,» says Reizis.
About half of
patients also have RA or other connective tissue diseases, such as
lupus.
The researchers
also noted that the region of the X chromosome containing Xist showed the biggest differences in expression when comparing
lupus to healthy
patients.
Margaret Shupnik, PhD, a Professor of Medicine at UVA's School of Medicine who
also worked with Jarjour's team says she hopes that the findings will prompt other researchers to develop novel therapies that regulate TLRs, and offer
lupus patients the kind of treatment options that they currently don't have.
Additional analyses revealed that the mice generated specific autoantibodies that were
also similar to those found in
lupus patients.
«Plaquenil was first used to treat malaria but was later found to
also have beneficial effects in
patients with inflammatory arthritis such as rheumatoid and
lupus,» said Dr. Steven Beldner.
Also, not all
Lupus patients have the same severity of the disease.»
The
patient takes immunosuppressant drugs that not only protect the new organ from future attacks, but
also helps keep
lupus in remission overall.
Lupus patients are
also prone to cardiodegenerative symptoms including anemia, high blood pressure, heart disease, shortness of breath, seizures and stroke.
According to estimates, about 6 % of
patients with
lupus also have hypothyroidism and 1 % hyperthyroidism.
Cortisol production is
also decreased in
lupus patients, explaining why they do better when treated with steroids.
Also, in my
patients with autoimmune disorders
Lupus, Rheumatoid Arthritis and other connective tissue disorders, I have seen concentrated soy protein isolates cause increases in pain, swelling and inflammation.
Shoulberg, 45, who has been practicing since 1984, says her
patients mostly suffer from allergies, but she's
also diagnosed skin and ear infections, and immune - system diseases like
lupus.