Whole genome and whole transcriptome sequencing of 31 pediatric Asian patients with T - cell acute
lymphoblastic leukemia found that about 10 percent had the same alteration in a non-coding region of DNA.
Not exact matches
«Role of RNA binding protein in driving cancer,
leukemia study reveals: Abnormally expressed in cancer cells, the protein was
found to promote the proliferation of B cells in B - cell acute
lymphoblastic leukemia.»
His group was the first to publish
findings of dramatic molecular remissions in patients with chemorefractory acute
lymphoblastic leukemia following treatment with autologous CD19 - targeted T cells.
[3]-RRB- However, the presence of the Philadelphia (Ph) chromosome is not sufficiently specific to diagnose CML, since it is also
found in acute
lymphoblastic leukemia [4](aka ALL, 25 — 30 % of adult cases and 2 — 10 % of pediatric cases) and occasionally in acute myelogenous
leukemia (AML).
Study
finds age, ancestry and genetics can influence the risk of pancreatitis, a serious chemo side effect in acute
lymphoblastic leukemia patients.
A possible targeted therapy is
found for a high - risk form of acute
lymphoblastic leukemia, the most common childhood cancer.
Ponatinib was not
found to show better or worse outcomes in in blast - crisis phase (BC)- CML, or in Philadelphia chromosome — positive acute
lymphoblastic leukemia (Ph + ALL).
Abnormally expressed in cancer cells, the protein was
found to promote the proliferation of B cells in B - cell acute
lymphoblastic leukemia
The new results — from trials for patients with advanced lymphoma, multiple myeloma, and pancreatic cancer — expand on Penn's work with chimeric antigen receptor (CAR) therapies, building on
findings in patients with chronic lymphocytic
leukemia and acute
lymphoblastic leukemia dating back to the start of the first clinical trial in 2010.
A group of researchers at the Baylor College of Medicine has published the results of a study in the journal PLoS ONE demonstrating that a concentrated form of the compound sulforaphane
found in broccoli and other cruciferous vegetables has been shown to reduce the number of acute
lymphoblastic leukemia cells in a lab setting.