A
lymphocyte is a type of white blood cell that helps protect our body from diseases. It is an important part of our immune system and fights against infections and harmful substances.
Full definition
Hoping to learn something about how the human body defends itself against cancer, he had zeroed in on a complex regiment
of lymphocytes called T cells, common to the immune systems in both mouse and man.
The role of B
lymphocytes in producing protective antibodies that are secreted into the intestine is well - recognized.
Antibodies, known generally as immunoglobulins, are made and secreted by
B lymphocytes in response to stimulation by antigens.
In 2006, a company called Imulan was granted a conditional license by the USDA to market a product for FLV + and FIV + cats
called Lymphocyte T - Cell Immunomodulator (LTCI).
Distinguishing cell recognition such
as lymphocytes from monocytes and numbers can be over or underestimated.
George Coukos and colleagues provide the first data indicating a relationship between tumor immunity and ovarian patient outcomes, reporting that the presence of tumor -
infiltrating lymphocytes in the primary tumor strongly correlated with patient survival.
Takano T, Hohdatsu T, Hashida Y, Kaneko Y, Tanabe M, Koyama H. 2007b A «possible» involvement of TNF - alpha in apoptosis induction in peripheral
blood lymphocytes of cats with feline infectious peritonitis.
However, given the heterogeneity of the innate -
like lymphocyte population, we can not exclude the possibility that LFA1 blockade also decreases retention of some cells within the LN parenchyma, thereby increasing their movement into the SCS.
Chuang, J. C., Yu, C. L., and Wang, S. R. Modulation of
human lymphocyte proliferation by amino acids.
Maria Schreiber: IL - 7 effects
on lymphocyte development and function in transplantation relevant models
When your body responds to the sudden stress of even just more long - term levels of anxiety, the white blood cell
lymphocyte proliferation reaches high levels of inflammation.
T and B
lymphocyte numbers were not significantly elevated in nictitans glands from dogs with neurogenic KCS compared with those in dogs with normal tear production.
Subsequent studies in animal models that are thought to mimic the human experience indicate RSV inactivated vaccine induces an increased CD4 + T
lymphocyte response, primarily of Th2 cells and the occurrence of immune complex depositions in lung tissues [32], [42], [43].
Researchers think it acts on another gene called
lymphocyte activation gene - III, located at the other end of the same chromosome.
The complete blood count panel showed no group changes in percentage of each type
for lymphocytes, neutrophils, eosinophils and basophils.
Among subgroup analyses, the study evaluated patients» human
lymphocyte antigen type, whether HLA - A1 or HLA - A2.
In addition,
mixed lymphocyte cultures using the cells of the chimeric animals as responder cells to donor splenocytes failed to demonstrate any sensitization or clonal deletion of alloreactive T cells; i.e. T cell responses were identical to those of control animals (n = 4)(data not shown).
His group defined a functional niche for B cells (around sinusoids in the bone marrow), identified the first two mutants that abrogate marginal zone B
lymphocyte development, developed the concept of a follicular versus marginal zone B lymphoid cell - fate decision, and discovered two new defined stages of peripheral B cell development, the marginal zone precursor (MZP) B cell, and the Follicular type II B cell.
Furthermore, there are two main types of
lymphocytes found in the body: B cells and T cells.
Although GMCSF is mostly known for its role in inflammation, Dr. Merad's laboratory discovered that GM - CSF is produced in the normal gut by specialized cells called
innate lymphocyte cells (ILCs) in response to microbiota signals.
(A) Human
tonsillar lymphocytes or (B) sorted Lin - CD127 + cells were pretreated with lethal toxin (1 μg / ml) for 2 — 3 hr followed by IL - 23 (50 ng / ml) stimulation for 18 hrs.
But occasionally there will be a hint of problems in the lymphatic system causing unusually shaped or abnormally
low lymphocyte numbers circulating in your pet's blood.
Hands - on experience with isolating, culturing, and expanding antigen -
specific lymphocytes from human whole blood
Treatment with VIC - 008
increased lymphocyte infiltration of tumors and both the levels and the anti-tumor response of CD8 T cells, which kill damaged or infected cells.
Segmented filamentous bacteria are indigenous intestinal bacteria that activate
intraepithelial lymphocytes and induce MHC class II molecules and fucosyl asialo GM1 glycolipids on the small intestinal epithelial cells in the ex ‐ germ ‐ free mouse
Neutrophil - to -
Lymphocyte Ratio Predicts Overall Survival of Advanced Non-Small Cell Lung Cancer Harboring Mutant Epidermal Growth Factor Receptor
[13] Effector sites include areas such as the lamina propria, exocrine gland stroma, and surface epithelia, where
mature lymphocytes perform their functions, such as releasing cytokines and secreting antibodies.
The presence of these larger - than -
normal lymphocytes in increased number (often with unusual stain colorations) indicates that your pet's immune system is responding to something.
They found that about 3 to 5 percent of
female lymphocytes expressed two copies of these genes, as well as two copies of a gene unrelated to immunity.
Dr. Alexander was previously Chairman of the Molecular Immunology Program and Head of the Laboratory of
Lymphocyte Signalling and Development at the Babraham Institute, Cambridge.
Stress
decreases lymphocyte cytolytic activity in the young monkey even after blockade of steroid and opiate hormone receptors
These groups of B
lymphocytes produce antibodies specially designed to fight the specific invader or turn into antibody - secreting cells and memory B cells that give long - term protection and help protect the next time the same pathogen is encountered.
When lymphocytes become cancerous within a lymph node, the node swells and hardens.
The first author Franziska Roth - Walter and her colleagues now show that an «empty» milk protein, one without iron and siderophores, helps to activate
Th2 lymphocytes.
Similarly, mice without
immunosuppressive lymphocytes hardly had any tumors, even at 11 months, presumably since their absence left the cytotoxic T cells alone to do their tumor - fighting job.
A research group led by Osaka University and the University of Turku has found for the first time that a lipid called lysophosphatidic acid (LPA) plays a vital role in regulating
lymphocyte motility within lymph nodes.
The response to anti-PD-1 was restored in germ - free as well as antibiotics - treated mice by introducing a diverse microbiome, and was driven by increased entry of tumor - infiltrating
lymphocytes into the tumor; specifically, CD8 + T effector cells.
Phrases with «lymphocyte»