Here we sought to quantify T and B
lymphocyte populations in the lacrimal tissue of the nictitans glands of dogs with iKCS those with neurological KCS (nKCS) and also in dogs with tear production within the recognized normal levels and no ocular surface signs of KCS.
Enhanced expression of one of these molecules, CD1d, is coupled to selective induction of invariant natural - killer T cells (iNKT), a subset of T lymphocytes that are present at low levels in
lymphocyte populations and whose absence enhances autoimmunity in animal models.
To develop new, targeted treatments to eliminate these residual infected cells, we need to find exactly where in the CD4 T
lymphocyte population the virus hides.
Using a mixed
lymphocyte population obtained from a mucosal tissue (tonsils) we treated cells with or without lethal toxin for 3 hr and then stimulated the cells with or without IL - 23.
However, given the heterogeneity of the innate - like
lymphocyte population, we can not exclude the possibility that LFA1 blockade also decreases retention of some cells within the LN parenchyma, thereby increasing their movement into the SCS.
In an effort to reveal a role of CD169 in sinus retention of the total innate - like
lymphocyte population, we blocked αL prior to blocking CD169.
Not exact matches
So scientists choose the
lymphocytes with the greatest tumor - fighting activity, grow a large
population of them in the lab, then infuse them back into the patient.
«In the laboratory we found that the two drugs wake up different
populations of CD4 + T
lymphocytes, thus waking up different reservoirs.
Events were gated as follows: singlets (FSC - A by FSC - H), live cells (SSC - A by Live / Dead),
lymphocytes (FSC - A by SSC - A), CD3 + CD4 + (CD3 by CD4), and then events were divided into CXCR4 + and CXCR4 -
populations based upon a fluorescence minus one (FMO) control.
Vα14 invariant NKT (Vα14 iNKT) cells are a
population of T
lymphocytes that have several unique characteristics; many of these are related to their ability to function similarly to cells of the innate as opposed to the adaptive immune system.
This project will determine whether specific
populations of
lymphocytes are required for RGC death in glaucoma.
The first Phase 1 study of this vaccine in a malaria - exposed
population found it to have promising safety and tolerability profiles in adults in Bandiagara, Mali, and to elicit dose - dependent anti-AMA1 antibody responses [17] as well as IL - 5 production and
lymphocyte proliferative responses [22].
«Recently, analyses of patients who received checkpoint blockade identified neutrophil - to -
lymphocyte ratio < 3 and normal lactate dehydrogenase as positive predictors of response; however, in our lymphodepleted patient
population, neither separated patients who achieved responses from those who did not clearly enough to warrant use as an inclusion criterion,» the researchers wrote.