Sentences with phrase «lymphocytes into»

Evans» team had previously shown that fever also assists the passage of lymphocytes into lymphoid tissue, but they hadn't figured out what was happening on a molecular level.

Instead of producing healthy lymphocytes, white blood cells that fight infections, his bone marrow was unleashing abnormal lymphocytes into his bloodstream.

Not exact matches

One of the types of cells called into action are T lymphocytes, a type of white blood cell that fights infection.

The role of B lymphocytes in producing protective antibodies that are secreted into the intestine is well - recognized.

So scientists choose the lymphocytes with the greatest tumor - fighting activity, grow a large population of them in the lab, then infuse them back into the patient.

His physician, David Golde of UCLA, found a rare T lymphocyte in Moore's blood that could be coaxed into making an immune - boosting protein.

The orbital remodeling in TED is likely induced by infiltrating T lymphocytes and mast cells, which activate orbital fibroblast effector cells to either proliferate and form scar - producing cells called myofibroblasts or turn into pro-inflammatory fat cells.

In addition, adds Dr. Ramiro, «after completing this program, the B lymphocytes can differentiate into plasma cells, which no longer proliferate but instead secrete large amounts of antibodies.

Immunologist Sharon Evans of Roswell Park Cancer Institute in Buffalo, New York, and coworkers are studying how fever affects the movement of white blood cells, or lymphocytes, from the blood into lymphoid tissue, where they learn to recognize and fight pathogens.

In mice with an artificial fever, more lymphocytes (green) adhered to blood vessels (red) in lymphoid organs and crossed the vessels into lymphoid tissue.

The implanted stromal cells attracted T and B immune cells (lymphocytes) that were already circulating in the healthy mouse, then organised them into compartments segregated from one another, just as they appear in natural nodes.

The lymphocytes quickly spread out from the artificial node into the animals» own lymph nodes, which lay empty due to the lack of immune activity.

Events were gated as follows: singlets (FSC - A by FSC - H), live cells (SSC - A by Live / Dead), lymphocytes (FSC - A by SSC - A), CD3 + CD4 + (CD3 by CD4), and then events were divided into CXCR4 + and CXCR4 - populations based upon a fluorescence minus one (FMO) control.

In laboratory experiments, Dr. Weinberger and his team inserted a green fluorescent protein, or «vector,» into the DNA of Jurkat T lymphocytes — a type of white blood cell that helps maintain a healthy human immune system.

Depletion of neutrophils blocks the recruitment of antigen non-specific cells into the liver without affecting the antiviral activity of hepatitis B virus - specific cytotoxic T lymphocytes.

Naïve T cells then expand and differentiate into effector T lymphocytes that acquire either cytotoxic activity or secrete high amounts of certain cytokines.

They include reduced lymphocyte repertoire, increasing clonality and increasing autoreactivity.5, 7,8 Recent work has focused on intrinsic cell defects, which alter T cell activation threshold, induction of cellular senescence and differentiation into short - lived effector or long - lived memory cells.

Spleen cells (3 × 107) from either experimental or control effector lymphocytes were dispensed into 75 - cm2 tissue culture flasks along with 20 ml of boosting medium and 6 × 105 γ - irradiated (3,000 rad) BALB / c spleen cells (erythrocytes lysed).

The iPSCs eventually turned into fully active, cancer - specific T - lymphocytes - in other words, cells that target and destroy cancer cells.

They started off with mature T - lymphocytes which were specific for a type of skin cancer and reprogrammed them into iPSCs with the help of «Yamanaka factors».

Depletion of neutrophils blocks the recruitment of antigen - nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus - specific cytotoxic T lymphocytes.

CD20 is a B - lymphocyte surface molecule that is widely expressed during B - cell ontogeny, from early pre-B-cell developmental stages until final differentiation into plasma cells.

Memory T cells can be triggered more readily than naive lymphocytes, which was not taken into account by pre-clinical animal experiments conducted thus far.

The researchers found higher levels of NCL - like lipofuscin in lymphoblasts, cells that mature into lymphocytes in patients with NCL, and also in asymptomatic patients carrying mutations in the progranulin gene.

These groups of B lymphocytes produce antibodies specially designed to fight the specific invader or turn into antibody - secreting cells and memory B cells that give long - term protection and help protect the next time the same pathogen is encountered.

We thaw them out onsite, we administer chemotherapy to eliminate the patient's normal lymphocytes, and then we infuse the thawed out reprogrammed CAR T cells into the patient, just like a blood transfusion.

These findings are in accord with the well - established roles of LFA1 and ICAM1 in supporting adhesion to and transmigration of lymphocytes across blood vessel endothelium into tissues (Rot and von Andrian, 2004).

Our conclusion that LFA1 and ICAM1 function during innate - like lymphocyte movement from the SCS into the LN parenchyma is based on four sets of observations in mice treated with αL blocking antibody: (1) innate - like lymphocytes transiently accumulate in the SCS; (2) the accumulated cells exhibit an unusual elongated morphology (suggesting a less adhesive state); (3) tracking analysis shows reduced numbers of cells migrating from the SCS into the parenchyma; (4) the cells are more sensitive to dislodgement by CD169 blocking antibody.

Visual inspection of the imaging data for FTY720 - treated versus control LNs suggested that there were fewer Cxcr6GFP / + innate - like lymphocytes in the SCS after FTY720 treatment and less examples of cells migrating into the sinus (Video 3).

However, given the heterogeneity of the innate - like lymphocyte population, we can not exclude the possibility that LFA1 blockade also decreases retention of some cells within the LN parenchyma, thereby increasing their movement into the SCS.

Colonic hydrotherapy, the process of irrigating the colon, was found to improve immune cell lymphocyte movement from the gut into the systemic (body) circulation, potentially improving immunity.

Now guys, it sounds like, right now, the recommendations that you're making would be to follow up this series of tests with yet another test, a lymphocyte subset panel, and then also look into something like enhancing my body's intake of glutathione or glutathione precursors along with, perhaps for this aldosterone side issue, adding in some sea salts and some trace minerals.

So we'll make sure there's a lot of other cofactors coz when you give iodine, it can spit out hydrogen peroxide, which can increase D cell lymphocyte infiltration into the thyroid.

Still going with a needle aspiration, and they poke it into the thyroid, they'll if the tissues have any lymphocyte infiltration.

Cruciferous vegetables — broccoli, Brussels sprouts, kale, cauliflower, cabbage — contain a phytonutrient that is transformed by our stomach acid into the key that fits into the Ah receptor locks on our intraepithelial lymphocytes, leading to their activation.

Lymphocytes are then broken down even further into B - and T - cells.

Antigens that make their way into the body or develop within our cells are recognized primarily by the lymphocytes produced by the thymus and bone marrow, or picked up as they pass through the secondary lymphatic organs.

As these lymphocytes get older, they're sent into the lymphatic vessels to hunt down and attacking infected or cancerous cells.

But even prior to all this, we had severe concerns about VLC / ketogenic diets: the very low triglycerides that these ketogenic dieters attain were being implicated in autoimmune pathogenesis in an Italian study; the mucin deficiency that you mention were also being linked to immune (Secretory IgA deficiency); the T - lymphocyte dysfunction was being linked to ketosis and its effect on thymus; and the general leukopenic effect that a VLC diet has on everyone — this was being attributed to inflammation reduction but we were seeing WBCs fall into the 2s in many people.

Immunity One cup of spinach contains over 337 % of the RDA of vitamin A that not only protects and strengthens «entry points» into the human body, such as mucous membranes, respiratory, urinary and intestinal tracts, but is also a key component of lymphocytes (or white blood cells) that fight infection.

Researchers from the University of Nebraska - Lincoln have generated an «on - off switch» into a weakened form of HIV, potentially creating a new vaccine for Human immunodeficiency virus; Scanning electron micrograph of HIV - 1 (in green) budding from cultured lymphocyte.

Then they migrate to the local lymph nodes where they present the antigens to other immune system cells (T lymphocytes) to stimulate them into a variety of activities to protect the body (immunity).

Hypothyroidism is triggered when the thyroid gland begins to waste away (called atrophy) or from a condition called lyphocytic inflammation, which is a condition where cells called lymphocytes enter the thyroid gland, and then turn normal tissue into fibrous tissue (fibrous tissue is common connective tissue in your dog's body).

Your pet's blood lymphocyte numbers can also go down when lymphocytes are lost into retained fluids (chylothorax) and in immune system malfunctions.

Virus, either free or lymphocyte associated, may enter the CNS by entering into mononuclear cells in the meninges, choroid plexus, epithelial cells of the fourth ventricle and ependymal cells lining the ventricular system.