Sentences with phrase «lymphocytic choriomeningitis virus»

«We discovered that when memory CD4 T cells were induced in the absence of antiviral CD8 responses or antibodies, they triggered an overwhelming inflammatory response in a mouse model of lymphocytic choriomeningitis virus [LCMV] infection,» explains senior author Dan Barouch, MD, PhD, director of the Center for Virology and Vaccine Research at BIDMC and Professor of Medicine at Harvard Medical School (HMS).

Wherry and his collaborators used PD - 1 knockout mice infected with lymphocytic choriomeningitis virus to see whether the genetic deletion of PD - 1 would be enough to prevent T cell exhaustion.

Vaxwave ® is based on lymphocytic choriomeningitis virus (LCMV) and in this vector the gene encoding the LCMV envelope protein, normally responsible for virus entry into target cells, has been deleted and replaced with a target gene of interest.

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice.

To conduct the study, Sanjabi and her team created a new model of viral infection through the rectum that uses lymphocytic choriomeningitis virus (LCMV), a rodent virus often used in research to model other pathogens.

The scientists validated their findings with another RNA virus called lymphocytic choriomeningitis virus (LCMV), which is a rodent virus often used in research to model other pathogens.

Platelets prevent IFN - a / b - induced lethal hemorrhage promoting CTL - dependent clearance of lymphocytic choriomeningitis virus.

Yet, after mice have beaten an infection with the lymphocytic choriomeningitis virus (LCMV), they remain immune — even long after the virus has vanished from their bodies.

In vivo, primary and secondary cytotoxic T cell responses against vaccinia and lymphocytic choriomeningitis virus were within normal ranges.

We studied the mechanism of lymphocytic choriomeningitis virus (LCMV) persistence and the suppression of cytotoxic T lymphocyte (CTL) responses in BALB / c WEHI mice infected at birth with LCMV Armstrong strain.

In this model, FHL is triggered by the lymphocytic choriomeningitis virus (LCMV), a virus that would normally be cleared by the CD8 T cell cytolytic response in perforin - sufficient mice.

Lymphocytic choriomeningitis virus (LCMV) infection of macaques: A model for Lassa fever.

Platelets prevent IFN - ab - induced lethal hemorrhage promoting CTL - dependent clearance of lymphocytic choriomeningitis virus.