Jimenez de Oya N *, De Giovanni M *, Fioravanti J, Ubelhart R, Di Lucia P, Fiocchi A, Iacovelli S, Efremov DG, Caligaris - Cappio F, Jumaa H, Ghia P, Guidotti LG, Iannacone M. Pathogen - specific B cell receptors drive chronic
lymphocytic leukemia by light chain - dependent cross-reaction with autoantigens.
Not exact matches
Among children, both acute
lymphocytic leukemia (ALL) and acute myeloid
leukemia (AML) are usually diagnosed in their acute form.4 From 1975 to 2011, the incidence rate of
leukemia increased in the United States
by an annual average of 0.7 % for children and adolescents aged 0 to 19 years, 5 while in the European Union, the yearly increase in
leukemia incidence between 1978 and 1997 averaged 0.6 %.6
By employing a translational approach and utilizing cutting - edge molecular tools, his research group has made outstanding contributions to our understanding of the mechanisms behind the development of chronic
lymphocytic leukemia (CLL), the most common adult
leukemia.
A year later, Carlo Croce, now director of the Human Cancer Genetics Program at Ohio State University, reported that chronic
lymphocytic leukemia (CLL), the most common form of the disease, was caused
by deletion of two microRNA genes.
Auranofin is being evaluated
by The Learning Collaborative as a treatment for relapsed chronic
lymphocytic leukemia (CLL).
Ofatumumab (Arzerra), a human anti-human CD20 monoclonal antibody to treat chronic
lymphocytic leukemia, is approved
by the FDA.
Using a novel technique to genetically modify T cells for adoptive transfer, Carl June, Michael Kalos, David Porter, Bruce Levine, and colleagues at the University of Pennsylvania School of Medicine achieve clinical responses in patients with chronic
lymphocytic leukemia, including two complete, durable (one year) clinical responses, accompanied
by in vivo expansion and long - term functional persistence of gene - modified cells.
Prognostic Value of ZAP - 70 Expression in Chronic
Lymphocytic Leukemia as Assessed
by Quantitative Polymerase Chain Reaction and Flow Cytometry.
Leukemia is a cancer of the bone marrow and blood and is classified
by cell type and rate of growth: acute
lymphocytic, chronic
lymphocytic, acute myeloid, and chronic myeloid.