Distribution of rotavirus - specific memory B cells in gut - associated
lymphoid tissue after primary immunization.
Induction of rotavirus - specific memory B cells in gut - associated
lymphoid tissue after intramuscular immunization.
Not exact matches
In contrast, examination of the same section of small intestine
after the infant is born and has begun breast - feeding reveals proliferating, mature epithelium with enterocyte differentiation and abundant
lymphoid tissue.
But the bottom line is that about two thirds of all T cells reside in the
lymphoid tissue of the gut, where the virus spreads
after exposure, even before it shows up in blood.
In pathological conditions, MSCs migrate preferentially into
lymphoid organs, allografts, injured and / or inflammatory
tissue sites
after systemic transfusion, where they interact with the activated immune cells and modulate their function 51, 52.
Only when the virus spread to the
lymphoid tissues did the systemic immune system begin to respond and control the virus, approximately one week
after infection.
After birth, lymphocytes are found in large numbers in the thymus and lymph nodes, and accumulate in collections of
lymphoid tissue in areas where foreign antigens are likely to enter the body.
After ingestion, the virus replicates in the
lymphoid tissues, and causes suppression of the immune system.