Sentences with phrase «lymphoma cell models»
Not exact matches
The researchers also affected mouse models with Mantle Cell Lymphoma, using the new platform to target cancer cells, induce cell death and dramatically improve overall surviCell Lymphoma, using the new platform to target cancer cells, induce cell death and dramatically improve overall survicell death and dramatically improve overall survival.
https://www.sciencedaily.com/
In a xenograft KMT2D - mutated T - lymphoma model, dual treatment with chidamide and decitabine significantly retarded tumor growth and induced cell apoptosis through modulation of the KMT2D / H3K4me axis.
The combination of hypomethylating agents and histone deacetylase inhibitors produce marked synergy in preclinical models of T - cell lymphoma
The in vivo anti-tumor activity of dual treatment on T - cell lymphoma was further evaluated in a murine xenograft model in which KMT2D V5486M mutated Jurkat cells subcutaneously injected into nude mice.
Kvansakul found that the viral protein blocks multiple pro-apoptotic proteins in host cells, and that in a mouse model of Burkitt lymphoma it also renders chemotherapy agents ineffective, making it a potent oncogene.
ONC201 combined with bortezomib in a Burkitt's lymphoma xenograft model reduced tumor cell density and improved CHOP induction compared to either agent alone.