Sentences with phrase «lymphoma cells using»

Her mentor was Lindsay Shopland, Ph.D., director of education and the research topic was stimulating proliferation of primary mantel cell lymphoma cells using a combination of MegaCD40L and IL4

Not exact matches

The researchers also affected mouse models with Mantle Cell Lymphoma, using the new platform to target cancer cells, induce cell death and dramatically improve overall surviCell Lymphoma, using the new platform to target cancer cells, induce cell death and dramatically improve overall survicell death and dramatically improve overall survival.
He is using the virus to cure a rare form of blood cancer called EBV lymphoma, caused when B lymphocyte immune cells get infected with the Epstein - Barr virus (EBV).
Westin launched his campaign last spring, and by the fall he had handed over management of his clinical trials — most recently testing the efficacy of a combination of three drugs used to treat large B - cell lymphoma — to colleagues.
The team used gene expression profiling and found that canine B - cell lymphoma expression profiles were similar in many ways to human B - cell lymphoma, thus paving the way for future studies, including therapeutic clinical trials in dogs and humans.
His group uses genome - wide and gene - specific DNA methylation analysis to identify aberrantly silenced tumor suppressor genes in B cell leukemias and lymphomas.
Based on our data, autologous stem cell transplant should be considered the standard of care for patients with HIV - related lymphomas for the same indications and under the same circumstances that we would use it in patients without HIV infection.»
Use of exon - based transcriptome profiling to identify novel signaling pathways and survival - associated genes in diffuse large B - cell lymphoma.
Optimizing Post-Allogeneic Hematopoietic Cell Transplant Outcomes for Lymphoma Using Ibrutinib
Plerixafor has been approved by the FDA as the first small - molecule CXCR4 antagonist for use in combination with granulocyte - colony stimulating factor (GCSF) to mobilize hematopoietic stem cells to the bloodstream for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma.
In the study, researchers at Case Western Reserve University School of Medicine gave mice mega-doses of bexarotene, a drug used to treat a type of skin cancer called cutaneous T - cell lymphoma.
It is well known that HDAC inhibitors are potent anticancer drugs in hematopoietic malignancies, including lymphoma.19 — 21 The aim of using HDAC inhibitors is to restore normal histone modification patterns through inhibition of various components of the epigenetic machinery.22, 23 In B - cell lymphoma, HDAC inhibitors can rescue deficits in histone acetylation induced by EP300 / CREBBP mutations, 24 rendering tumor cells more sensitive to suberoylanilide hydroxamic acid.25 This can explain why chidamide also has favorable efficacy on PTCL - NOS patients bearing EP300 / CREBBP mutations.
The therapy, produced by Kite Pharma and owned by Gilead Sciences, is approved for use against some types of large B - cell lymphomas.
(B) KMH2 Hodgkin's lymphoma cells were inhibited in vivo for 33 — 36 hours using the indicated concentration of RIPK2 inhibitor 1.
(A) Immunoblot illustration of the use of RIPK2 phospho - antibodies in two Hodgkin's lymphoma cells that have constitutive active RIPK2.
The use of anti-CD19 chimeric antigen receptor T cells induced a nearly sixfold higher rate of complete response compared with historical outcomes in patients with refractory, aggressive non-Hodgkin lymphoma.
Vaccination of patients with b - cell lymphoma using autologous antigen - pulsed dendritic cells
This is most commonly used in intestinal small cell lymphoma.
bone marrow or blood cell cancers such as lymphoma) Used in immune - mediated conditions (ex.
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