Sentences with phrase «lysine methyltransferase»
«Mammalian histone lysine methyltransferase, suppressor of variegation 39H1 (SUV39H1), initiates silencing with selective methylation on Lys9 of histone H3, thus creating a high - affinity binding site for HP1.
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The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
A chemiluminescence - based method for identification of histone lysine methyltransferase inhibitors.
Liu, F.; Chen, X.; Allali - Hassani, A.; Quinn, A. M.; Wasney, G. A.; Dong, A.; Barsyte, D.; Kozieradzki, I.; Senisterra, G.; Chau, I.; Siarheyeva, A.; Kireev, D. B.; Jadhav, A.; Herold, J. M.; Frye, S. V.; Arrowsmith, C. H.; Brown, P. J.; Simeonov, A.; Vedadi, M.; Jin, J. Discovery of a 2,4 - diamino -7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a.
Researchers discover that the inhibition of a lysine methyltransferase allows for the long - culture and amplification of human muscle stem cells
Chris Vakoc Chromatin; transcriptional regulation; acute myeloid leukemia; BET bromodomains; lysine methyltransferases
Discovery of an in Vivo Chemical Probe of the Lysine Methyltransferases G9a and GLP; Feng Liu, Dalia Barsyte - Lovejoy, Fengling Li, Yan Xiong, Victoria Korboukh, Xi - Ping Huang, Abdellah Allali - Hassani, William P. Janzen, Bryan L. Roth, Stephen V. Frye, Cheryl H. Arrowsmith, Peter J. Brown, Masoud Vedadi, and Jian Jin; J. Med.
Not exact matches
Mechanistically, we observed that Wnt / ß - catenin signaling orchestrates the cytoplasmic relocalization of the histone 3 lysine 9 methyltransferase Setdb1 during differentiation.
The histone 3 lysine 4 methyltransferase, Mll2, is only required briefly in development and spermatogenesis.
Tachibana, M.; Sugimoto, K.; Nozaki, M.; Ueda, J.; Ohta, T.; Ohki, M.; Fukuda, M.; Takeda, N.; Niida, H.; Kato, H.; Shinkai, Y. G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis.
Li, Y.; Reddy, M. A.; Miao, F.; Shanmugam, N.; Yee, J. - K.; Hawkins, D.; Ren, B.; Natarajan, R. Role of the Histone H3 Lysine 4 Methyltransferase, SET7 / 9, in the Regulation of NF --LCB- kappa -RCB- B - dependent Inflammatory Genes: RELEVANCE TO DIABETES AND INFLAMMATION.