Sentences with phrase «lysine residues in»

Not exact matches

To date, only two residues involved in forming ubiquitin chains, lysine 48 and lysine 63, have been linked to autophagy.

The new system allowed the team to add a third residue — lysine 33 — to ubiquitin's repertoire in controlling this cellular housekeeping system.

They next undertook targeted sequencing of the lysine - 27 residue in all 16 genes that code for H3 isoforms in a validation cohort comprising 43 DIPGs and 36 non-brainstem glioblastomas.

Substrate peptides used in this assay were: the first 25 residues of histone 3 [H3 (1 - 25)-RSB- for G9a, EHMT1 and SETD7 at 10, 20 and 100 µM respectively; the first 24 residues of histone 4 [H4 (1 - 24)-RSB- at 10 and 500 µM for PRMT3 and SETD8 respectively; and H3K9Me1 [H3 (1 - 15), monomethylated at lysine 9] at 200 µM for SUV39H2.

He introduced a number of important techniques in chemical modification of proteins, in particular based on reversible amidination and trifluoroacetylation of lysine residues.