Sentences with phrase «lysosomal system»

Not exact matches

The drug candidate is intended for the treatment of subjects with neuronal ceroid lipofuscinosis, aka Batten Disease, a fatal lysosomal storage disease that primarily affects the nervous system in children.

Both MPS IIIA and GM1 are classified as neuropathic (i.e. affecting the central nervous system) Lysosomal Storage Disorders, a group of approximately 50 rare inherited metabolic disorders that result from defects in lysosomal Lysosomal Storage Disorders, a group of approximately 50 rare inherited metabolic disorders that result from defects in lysosomal lysosomal function.

They soon concluded that the same selective lysosomal degradation pathway was used in both systems, even when breaking down completely different proteins.

The 4 primary intracellular pathways that contribute to the regulation of skeletal muscle proteolysis are the autophagy / lysosomal, calpain - dependent, caspase - mediated, and ubiquitin proteasome (UP) systems.

It's a metabolic storage disorder resulting in lysosomal enzyme deficiency, which affects nearly every system in the dog's body.