Sentences with phrase «lysosomes also»
Indeed, mutations in multiple lysosomal genes result in severe neurodegeneration and it is becoming more clear that lysosomes also play a neuroprotective role in more common neurodegenerative diseases such as Alzheimer's disease that have not traditionally been associated with lysosomal defects.
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CUET proteins also associate with specific cellular structures that target the whole complex to the cellular waste disposal and recycling station, the lysosome.
Dr. Huizing is also investigating the causes of and potential treatments for disorders of lysosome - related organelles (LROs), including Hermansky - Pudlak syndrome (HPS), Chediak - Higashi syndrome, and Griscelli syndrome.
Lysosomes are also often located close to the Golgi apparatus, but they are larger and more densely stained.
There is also another mechanism by which cellular amino acid nutrition impacts on mTOR signalling; this involves the amino acids generated within the lysosomes by intracellular protein degradation and autophagosomal digestion [23,24].