Sentences with phrase «mabs induced»
Furthermore, anti-CD3 mAb induced phosphorylation of ERK, phospholipase C γ (PLC - γ), and SLP76, all were unaltered in Gasp - deficient DP thymocytes (Fig. 5F).
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These findings highlight the need to (a) induce multiple neutralizing antibody lineages for a protective antibody - based vaccine and (b) the potential need to use combinations of purified mAb in therapeutic or prophylactic settings.
Finally, his discussion covers the genetic manipulation of induced pluripotent stem cells (iPSCs) to derive NK cells engineered to express modified CD16A, and their potential for improving the efficacy of tumor - targeting therapeutic mAbs.