Sentences with phrase «mrna coding sequences»

While the two actin isoforms differ by only four amino acids, their mRNA coding sequences differ by almost 13 percent because of «silent» nucleotide differences that nevertheless encode the same amino acids.

Not exact matches

«By sequencing all of the DNA that codes for mRNA and ultimately, proteins, Dr. Amin and colleagues found a single gene that may account for as much as 4 % of the heritable risk for depression,» said Doctor John Krystal, Editor of Biological Psychiatry.

In the new study, the researchers show that Stau2 binds specifically to a so - called intron sequence found near the end of a specific subset of mRNAs — in a region that contains no coding information, but serves a regulatory function instead.

This results in the inclusion of extra coding sequences in the mRNA, which when translated, end up producing malfunctioning haemoglobin molecules.

In order to reach maturation and be sent to the cellular «machine» that deals with protein synthesis, the non-coding fragments contained in the mRNA, the introns, need to be removed, whereas the coding sequences, the exons, have to be linked together.

Now, John Chaput and his colleagues at Arizona State University's Biodesign Institute have produced the first genome - wide investigation of cap - independent translation, identifying thousands of mRNA sequences that act as Translation Enhancing Elements (TEEs), which are RNA sequences upstream of the coding region that help recruit the ribosome to the translation start site.

Scientists have found a group of human sequences — unrelated to those in mice — which are capable of producing SINEUPs, which can pair with typical protein - coding mRNAs and enhance their translation.

Two adenovirus mRNAs have a common 5 ′ terminal leader sequence encoded at least 10 kb upstream from their main coding regions