Sentences with word «macroautophagy»

Rapid parallel measurements of macroautophagy and mitophagy in mammalian cells using a single fluorescent biosensor.

Then non-selective macroautophagy of the cytosol leads to accumulation of Pho8Δ60 in the vacuole, where it is cleaved to generate an active enzyme.

Autophagy (more specifically macroautophagy) is the process by which cellular compartments, such as membranes and organelles and also protein aggregates, are recycled back into their building blocks [122].

During macroautophagy, cells form double membrane - bound vesicles, autophagosomes, that sequester organelles, proteins or portions of the cytoplasm for delivery to the lysosome [123].

Here we show that lysosomal pathology in AD brain involves extensive alterations of macroautophagy, an inducible pathway for the turnover of intracellular constituents, including organelles.