Sentences with word «macrocycle»

The outermost groups also fine - tune the properties of macrocycles.

Before the work described in the Science paper, there was no way to systematically design ordered peptide macrocycles like cyclosporine.

The rotelle - shaped molecule — known as a «pi - conjugated spoked - wheel macrocycle» — acts the opposite of polarizing sunglasses, which screen out glare reflected off water and other surfaces and allow only direct sunlight to enter the eyes.

Poly [n] catenanes, where the molecular chains consist solely of interlocked macrocycles, contain one of the highest concentrations of topological bonds.

Manning, HC., Bai, M., Anderson, BM., Lisiak, R., Samuelson, L., Bornhop, D.J. Expeditious synthesis of P - Protected macrocycles in - route to lanthanide chelate metal complexes.

The old Eastern «conjugate sequence» system I typically refer to is more akin to block periodization, where separate aspects of athleticism are built at distinct times during the training macrocycle, and varying specific strength exercises are used in conjunction with the technical (sports - specific) movements to build technique.

The methods covered in the report, «Comprehensive computational design of ordered peptide macrocycles» now solve these problems.

Haem, for example, consists of four pyrrole - type rings joined by carbon bridges to form a larger ring system called a macrocycle which consists of 20 carbon atoms and 4 nitrogen atoms.

The way other groups are arranged on the macrocycle shows the family relationship between the pigments of life.

The key was using zinc ions to template the threading of one macrocycle precursor through flanking preformed macrocycles, after which metathesis catalysis closed up the first ring, and the metal could be flushed out.

The prototype of such bis - macrocycles, plerixafor, was used in a recent study as a starting point for structural modification, in order to identify compounds endowed with a similar antiviral activity and improved pharmacokinetic properties [94].

During her PhD studies she has been involved in projects with different applications but with a main objective of investigating the conformational behaviour and the intramolecular interactions of cyclic peptides and macrocycles.

A C2 - symmetric cyclohexyldiamine macrocycle directs the assembly of the

The birds - eye view of a periodized program is your whole training year (the macrocycle).

Macro, Meso and Micro Cycles an overview of Periodisation and how to align microcycles, mesocycles and macrocycles.