Sentences with phrase «macrolides in»

Heavy use of macrolides in the first two years of life was also associated with an increased risk of asthma later in life.

Not exact matches

Researchers are interested in using these natural antibiotics and the microbes that produce them in order to develop new antibiotics; however, microbes that produce antibiotic macrolides only make small amounts of a limited variety of antibiotics.

In E. coli, MphR can detect the presence of macrolide antibiotics being secreted by microbes that are attacking E. coli.

The researchers created a large library of MphR protein variants and screened them for the ability to switch on production of a fluorescent green protein when they were in the presence of a desired macrolide.

To help on this front, in a new paper published in the journal Structure, researchers from McGill University present in atomic detail how specific bacterial enzymes, known as kinases, confer resistance to macrolide antibiotics, a widely used class of antibiotics and an alternative medication for patients with penicillin allergies.

In one instance, the investigators discovered a novel gene conferring resistance to the macrolide antibiotics, which was a small 61 residue proline - rich peptide, said Topp.

«In the end, we now know exactly how superbugs confer resistance to macrolides using these kinases,» explains Dr. Berghuis.

The researchers found that the kinase enzymes have an impressive ability to confer resistance to many different macrolide antibiotics — the two enzymes that were studied in detail are essentially able to confer resistance to all macrolide antibiotics currently in use.

Macrolides appear to promote also the development of antibiotic resistance, as the resistance to these antibiotics was elevated in the microbiota of children who had used them.

An average of 80 cases of rapid heartbeat that can result in sudden cardiac death (or «ventricular tachyarrhythmias») occurred per 1 million treatment courses among patients who were not taking macrolides, the investigators found.

To put the findings into perspective, one in 8,500 patients treated with macrolides could develop a serious heart rhythm problem and one in 30,000 might die, Dr. Sami Viskin, from the Tel Aviv Medical Center and Sackler School of Medicine at Tel Aviv University in Israel, explained in an accompanying journal editorial.

Microfilariae are usually detectable in infected canids not receiving macrolide prophylaxis.

Tylosin is a macrolide - class broad spectrum antibiotic that's used in veterinary medicine to treat felines, canines and livestock.

Pets known to have had an allergic reaction to macrolide antibiotics Use with caution in pets with liver disease Breeding, pregnant and nursing animals (safety is unknown) Directions:

Drugs such as Tetracyclines, penicillin, and macrolides bring long term relief from symptoms, but do not completely remove the infection from your dog's body, but brings the levels down to where symptoms in most dogs do not reappear.