Sentences with phrase «macromolecular function»
The structural analysis guides further mutagenesis and biochemical experiments in both reconstituted systems in vitro and in primary cells, to finely analyze the mechanisms that mediate macromolecular function, or lead to a pathological dysfunction.
http://research.hsr.it/ Not exact matches
A partial list would include the Patterson function, isomorphous replacement, and anomalous scattering, which enabled the determination of organic structures; direct (i.e., purely computational) methods of phase determination, which enabled small - molecule crystallography to be almost totally automated; synchrotron radiation and area detectors, which together made it possible to collect data on macromolecular structures in hours instead of months; and automatic interpretation of electron density maps.
We will continue to study the relationship between the 3D structure and the function of macromolecular complexes using a combination of 3D Electron Microscopy, Cryo - Electron Tomography, single particle analysis, correlative fluorescence microscopy, image analysis, and needed biochemical techniques.
Proteins: Concepts in Biochemistry teaches the biochemical concepts underlying protein structure, evolution, stability, folding, and enzyme kinetics, and explains how interactions in macromolecular structures determine protein function.
The journal strives to be essential reading for structural biologists, as well as biologists and biochemists that are interested in macromolecular structure and function.
Information on the structure of macromolecules is important for biology and medicine because the function of many important biological processes can be directly linked to macromolecular structure or changes therein.
A) To enable protein structure elucidation of membrane proteins the primary target of most therapeutics and large macromolecular complexes such as viruses; B) Design proteins with novel structure and / or function to explore novel approaches to protein therapeutics and deepen our understanding of protein folding pathways.
Protein Structure - Function and Protein Folding; Structural Biology and Macromolecular Assemblies; Cryo - electron Microscopy and Tomography...
London, Cambridge, Tokyo, USA About Blog The scope of Polymer Chemistry includes the following: Novel synthetic and polymerization methods, Polymerization mechanisms and kinetics, Advanced characterization of polymers, Macromolecular structure and function, Synthesis and application of novel polymers for bio - / nanomedicine, Reactions and chemistry of polymers.