London, Cambridge, Tokyo, USA About Blog The scope of Polymer Chemistry includes the following: Novel synthetic and polymerization methods, Polymerization mechanisms and kinetics, Advanced characterization of polymers,
Macromolecular structure and function, Synthesis and application of novel polymers for bio - / nanomedicine, Reactions and chemistry of polymers.
Information on the structure of macromolecules is important for biology and medicine because the function of many important biological processes can be directly linked to
macromolecular structure or changes therein.
Crystallography and NMR system: a new software suite for
macromolecular structure determination
The journal strives to be essential reading for structural biologists, as well as biologists and biochemists that are interested in
macromolecular structure and function.
Topic: Automated
macromolecular structure solution from SAD and MR - SAD experiments with Crank2 Presenter: Navraj Pannu, Assistant Professor Leiden University, The Netherlands Host: Jason Key Recorded on March 8, 2016
(Collaborative Computational Project, Number 4) a collection of programs and associated data and software libraries used for
macromolecular structure determination by X-ray crystallography.
Therefore, before publication, large data sets (including microarray data, protein or DNA sequences, atomic coordinates or electron microscopy maps for molecular and
macromolecular structures, and climate data) must be deposited in an approved database and an accession number or a specific access address must be included in the published paper.
Molecular dynamics was used to refine
macromolecular structures by incorporating the difference between the observed crystallographic structure factor amplitude and that calculated from an assumed atomic model into the total energy of the system.
A partial list would include the Patterson function, isomorphous replacement, and anomalous scattering, which enabled the determination of organic structures; direct (i.e., purely computational) methods of phase determination, which enabled small - molecule crystallography to be almost totally automated; synchrotron radiation and area detectors, which together made it possible to collect data on
macromolecular structures in hours instead of months; and automatic interpretation of electron density maps.
His research focuses on the development of algorithms for determination of
macromolecular structures and determining structures of proteins from pathogenic organisms He is a member of the Phenix software development team.
Proteins: Concepts in Biochemistry teaches the biochemical concepts underlying protein structure, evolution, stability, folding, and enzyme kinetics, and explains how interactions in
macromolecular structures determine protein function.
Talks will discuss the origination of novel cell type gene regulatory networks, and cover the latest research into the evolution of cell type functional modules, such as protein complexes and larger
macromolecular structures.
Not exact matches
As researchers gradually gain more insight into the genome's hierarchy of
structures, they will get closer to figuring out how this
macromolecular wonder works in all of its vastness and mechanistic detail.
Because of the complex
structure of spider silk, large scale synthetic production still remains a challenge and can only be achieved through a controlled self - assembly of the
macromolecular components with nanoscale precision [2].
Single - particle cryoelectron microscopy (cryoEM) is now able to provide
structures of
macromolecular assemblies to resolutions approaching 3 Å, sufficient to allow the polypeptide chain fold to be traced in a number of cases.
The main experimental technologies that Instruct offers are complementary, and increasingly link detailed atomic
structure of single molecules or
macromolecular complexes with their cellular context.
We will continue to study the relationship between the 3D
structure and the function of
macromolecular complexes using a combination of 3D Electron Microscopy, Cryo - Electron Tomography, single particle analysis, correlative fluorescence microscopy, image analysis, and needed biochemical techniques.
The discovery driven group, PETRO Case Consortium at Case Western University, a Park AFM user, investigates the area of molecular,
macromolecular, and supramolecular synthesis and
structure of polymers and nanomaterials capable of controlled - assembly to form ultrathin films and dispersions with the aim of finding new technologies and materials that improve and replace established oil and gas field formations.
Martin Friedlander, M.D., Ph.D., is a professor in the Department of Cell Biology and the Graduate Program in
Macromolecular and Cellular
Structure and Chemistry at The Scripps Research Institute.
The main experimental technologies that Instruct - ERIC offers are complementary, and increasingly link detailed atomic
structure of single molecules or
macromolecular complexes with their cellular context.
A) To enable protein
structure elucidation of membrane proteins the primary target of most therapeutics and large
macromolecular complexes such as viruses;
Structural Biology Group The group consists of two laboratories focused on the use of
macromolecular crystallography (Barry Stoddard and Roland Strong) to determine the three - dimensional
structures of biological macromolecules.
A) To enable protein
structure elucidation of membrane proteins the primary target of most therapeutics and large
macromolecular complexes such as viruses; B) Design proteins with novel
structure and / or function to explore novel approaches to protein therapeutics and deepen our understanding of protein folding pathways.
Protein
Structure - Function and Protein Folding; Structural Biology and
Macromolecular Assemblies; Cryo - electron Microscopy and Tomography...