Not exact matches
«But they can not
do this in the complex
macromolecules we make because with so many block copolymer arms formed, there is no space.
I personally won't get excited about that until its practitioners can
do it for large oligomeric proteins — which includes being able to predict what kind of oligomer any given
macromolecule will form — and can also predict how a
macromolecule's conformation changes when substrate or another
macromolecule binds to it.
However, for
macromolecules, these techniques
do not yield an overall high - resolution description of the structure.
There are some standard sorts of checks that people tried to
do — e.g., compare to the atomic positions found by experimentalists in really - well - studied
macromolecules.