Sentences with phrase «macromolecules in»

This defect impairs the breakdown of complex molecules resulting in abnormal accumulation of this macromolecules in the cells of the peripheral and central nervous system.

A number of CNS pathologies, inclusive of neurodegenerative diseases incur increased BBB permeability and dysfunction, and this loss of a protective barrier allows relatively free entry of circulating blood macromolecules in the CNS.

In fact, the macromolecules in the CSF are actively transported by the capillary endothelium from brain to blood.

Not exact matches

One - celled microorganisms, in developing their metabolism, will depend in turn upon whatever macromolecules are available, so we should expect every world to have its own way of organizing simple living systems.

This is to say each of us has in our brains about as many macromolecules as there have been seconds since our part of the cosmos began to assume its present form.

Professor Paul Weiss (1969) has put this very dramatically by pointing out that the average cell in our bodies contains about 105 macromolecules.

The guiding principle in the field today is (in the words of chemist Cyril Ponnamperuma) that «there are inherent properties in the atoms and molecules which seem to direct the synthesis in the direction most favorable» for producing the macromolecules of life.

For example, after the macromolecules of amino acids or nucleic acids have become sufficiently abundant, the possibility of living cells becomes a relevant new form of ordered novelty in the world's advance.

less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)

The colostral stage is further characterized by high abundance of mRNAs (CTSD, CTSB, PSAP) that encode proteins involved in macromolecule catabolism (Table 3).

Scientists have shifted from studying single molecules to investigating large complexes of interacting biological macromolecules involved in processes such as metabolic pathways, gene expression, and development of disease.

Macromolecules abound in nature, and PG5 is about the same size as a tobacco mosaic virus.

In one project published recently in the journal Macromolecules, the Lipomi lab discovered that polymers with strings of seven carbon atoms attached produce exactly the right balance of stretchability and functionalitIn one project published recently in the journal Macromolecules, the Lipomi lab discovered that polymers with strings of seven carbon atoms attached produce exactly the right balance of stretchability and functionalitin the journal Macromolecules, the Lipomi lab discovered that polymers with strings of seven carbon atoms attached produce exactly the right balance of stretchability and functionality.

«But they can not do this in the complex macromolecules we make because with so many block copolymer arms formed, there is no space.

The formation of different phases during drying leads to dramatically different fluid movement and solid deposition and also provides insight needed for the control of drying solutions of macromolecules that occur in many dyes and pharmaceutical formulations.

They are stronger than steel, but the most important uses for these threadlike macromolecules may be in faster, more efficient and more durable electronic devices

Recent research findings were detailed in a paper published online in May in the journal Macromolecules.

The DNA which carries genetic information in cells is normally packaged in the form of one or more large macromolecules called chromosomes.

Next, they removed large macromolecules like antibodies as well as salt fragments, and discarded all molecules that exert their biological effects through mechanisms other than protein - ligand interactions, are not used to treat diseases or are found only in topical products.

«Because we can see individual macromolecules moving about in a living cell, we can study chemistry at a single - molecule level and in real life.

«More into detail, we found out that in viscous environments, of which living cells are an example, the mobility of produced macromolecules like proteins declines.

In this way, an analysis can be made as to what happens when the researchers «play» with the basic ingredients of the ice cream: cream, egg yolk, sugar, milk and thickening agents like gums or hydrocolloids, macromolecules that give the product thickness and stability.

These tubes function as biological pipelines that transport and deliver life - sustaining liquids, gases or macromolecules from one site in the body to another.

Be it snow on a slope that can sit there for days before being sent descending by an overambitious skier or bonds in macromolecules that change dramatically upon appropriate activation — systems that reside for extended periods of times in one state before switching rapidly to another, energetically more favourable one are found in many different contexts.

The novel process they developed and their results, which could help the world deal with its agricultural and plastic waste problems, appear in the ACS journal Macromolecules.

«We found that the perfect signal, p - coumaric acid, is in everything that bees eat — it's the monomer that goes into the macromolecule called sporopollenin, which makes up the outer wall of pollen grains.

It was after discussions with Max Perutz during his time in Cambridge that Doty made the critical decision to apply his unique knowledge of polymer science to the investigation of biological macromolecules.

The unit study macromolecules that are central in basic processes of cellular life, as well as for specific human pathologies.

As the smallest structural change in the scale of biological world, the isomerization and the catalysis of this reaction by isomerases is of great interest, to bridge the dynamics of chemical bonds and the biological functions of the macromolecules.

Structural refinements of proteins have become essential in order to understand the function of these biological macromolecules.

Host: Dr. Tim Murphy Speaker: Dr. Leonard Khiroug, Neurotar Title: In vivo two - photon imaging of fluorescently - labeled macromolecule penetration through blood - brain barrier: applications in Pharma preclinical studiIn vivo two - photon imaging of fluorescently - labeled macromolecule penetration through blood - brain barrier: applications in Pharma preclinical studiin Pharma preclinical studies

It is an original set - up for laboratory astrophysics dedicated to the study of the photophysics and chemistry of macromolecules and nanograins in interstellar conditions.

He is investigating both how the genome is packaged, protected, sequestered, and made accessible within the cell nucleus, as well as how changes in DNA sequence relates changes in structure and function of encoded biological macromolecules.

For her work in the field of macromolecule synthesis, she was awarded with the Otto Hahn Medal of the Max Planck Society (2002), an ERC Synergy grant (2012, together with Martin Plenio and Fedor Jelezko) and the Wissenschaftspreis of the city of Ulm (2014).

In 2017, she became Director at the Max Planck Institute for Polymer Research, where he is heading the Department «Synthesis of Macromolecules.

Her current research interests include the synthesis of functional macromolecules to address current challenges in biomedical and materials research.

In 2008 he was elected as member of the International Academy of Quantum Molecular Science, whose members are chosen among the scientists of all countries who have distinguished themselves by the value of their scientific work, their role of pioneers or leaders of a school in the broad field of the application of quantum mechanics to the study of molecules and macromoleculeIn 2008 he was elected as member of the International Academy of Quantum Molecular Science, whose members are chosen among the scientists of all countries who have distinguished themselves by the value of their scientific work, their role of pioneers or leaders of a school in the broad field of the application of quantum mechanics to the study of molecules and macromoleculein the broad field of the application of quantum mechanics to the study of molecules and macromolecules.

CERM / CIRMMP offers access to state of the art NMR instrumentation and expertise to perform, at the highest level, the most comprehensive array of experiments needed for the structure and dynamic characterization of biological macromolecules and their complexes in solution and at solid state.

Two retractions just appeared in Macromolecules (American Chemical Society): http://pubs.acs.org/doi/full/10.1021/acs.macromol.7b00492 http://pubs.acs.org/doi/full/10.1021/acs.macromol.7b00493 The other two are mentioned in the retraction notice.

First you need to use up what's in your direct transaction account (preferred macromolecules)-- starting with creatine phosphate and glycogen.These provide quick energy for short - term, high - intensity exercise, or fuel for the early stages of moderate - intensity workouts.

Although a non - essential amino acid in normal cells, the demand for glutamine is dramatically increased throughout malignant transformation to support increased metabolic demands; namely, provision of catabolic substrates for ATP production and anabolic substrates for macromolecule biosynthesis.The intracellular glutamine pool is also critical for sustained activation of mTORC1 signalling, a master regulator of cell growth and protein translation, as well as prevention of apoptosis

The authors of the in vitro study state, «Based on our results, we concluded that gliadin activates zonulin signaling irrespective of the genetic expression of autoimmunity, leading to increased intestinal permeability to macromolecules» (Drago et al., 2006, p. 408).

Tight junctions, regulated by a molecule called zonulin, as well as by conformational changes in the proteins occludin and claudin, are dynamic intercellular structures that modulate the trafficking or passage of macromolecules from the intestinal lumen to the submucosa and into systemic circulation (Fasano, 2012).

In a nut shell, leaky gut syndrome (LGS) describes a condition of altered or damaged bowel lining, caused by antibiotics, toxins, poor diet, parasites or infection can lead to increased permeability of the gut wall to toxins, microbes, undigested food, waste or larger than normal macromolecules.

Zonulin is the only physiologic modulator of intercellular tight junctions described so far that is involved in trafficking of macromolecules and, therefore, in tolerance / immune response balance.

Macromolecules such as starch, cellulose or proteins can not be rapidly taken up by cells and must be broken into their smaller units before they can be used in cell metabolism.

Enzymes that break down polymeric macromolecules into their smaller building blocks, in order to facilitate their absorption by the body.

Basically, it means that the gaps in between the epithelial cells of the intestine have become wide enough to allow the passage of large macromolecules, undigested foods, toxins and bacteria.

«Digestive enzymes are proteins that break down food macromolecules into their smaller building blocks in order to facilitate their absorption into the body through the gut lining,» says Dr. Vincent Pedre, author of Happy Gut.

[3] Parlesak A, Schäfer C, Schütz T, Bode JC, Bode C. Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol - induced liver disease.