Sentences with phrase «macrophage colony»

Macrophage colony - stimulating factor (M - CSF) is reported to enhance a variety of functions of mature monocyte / macrophages in vitro.

Idiotype / granulocyte - macrophage colony - stimulating factor fusion protein as a vaccine for b - cell lymphoma

T - VEC, recently approved for the treatment of advanced melanoma, is an oncolytic herpes simplex virus type 1 engineered to replicate selectively in tumor cells and express human granulocyte - macrophage colony - stimulating factor.

Primary overall survival from OPTiM, a randomized phase III trial of talimogene laherparepvec (T - VEC) versus subcutaneous granulocyte - macrophage colony - stimulating factor (GM - CSF) for the treatment of unresected stage IIIB / C and IV melanoma.

[8] Other agents of mostly historical interest include intralesional interleukin (IL), interferon (IFN), and granulocyte - macrophage colony - stimulating factor (GM - CSF), which have not shown consistent or durable efficacy and have not been rigorously tested in randomized trials.

Granulocyte - macrophage colony - stimulating factor, commonly referred to as GM - CSF, is a type of cytokine that stimulates the bone marrow to make more immune cells and blood cells.

However, some reports show that MSC do constitutively express mRNA for cytokines such as IL - 6, -7, -8, -11, -12, -14, -15, -27, leukaemia inhibitory factor, macrophage colony - stimulating factor, and stem cell factor 148, 149.

Oxidant - mediated mitochondrial injury in eosinophil apoptosis: enhancement by glucocorticoids and inhibition by granulocyte - macrophage colony - stimulating factor.

Drew Pardoll, Glenn Dranoff, Elizabeth Jaffee, Hyam Levitsky, and colleagues conduct preclinical studies showing that a vaccine composed of tumor cells irradiated and genetically modified to produce immune system growth factor GM - CSF (granulocyte - macrophage colony - stimulating factor)-- which would become known as the therapeutic cancer vaccine GVAX — could induce potent, specific, and long - lasting anti-tumor immunity in multiple mouse tumor models.

Antonio Lanzavecchia finds that efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte / macrophage colony - stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

Timed sequential treatment with cyclophosphamide, doxorubicin, and an allogeneic granulocyte - macrophage colony - stimulating factor - secreting breast tumor vaccine: a chemotherapy dose - ranging study of safety and immune activation.

Granulocyte macrophage colony - stimulating factor — secreting allogeneic cellular immunotherapy for hormone - refractory prostate cancer.

Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte - macrophage colony stimulating factor.

Researchers at Emory University School of Medicine were testing whether GM - CSF (granulocyte - macrophage colony stimulating factor), already used to restore white blood cell numbers during cancer treatment, could help heal blood vessels damaged by atherosclerosis.

Joseph Poole, M.D., Ph.D., of the Emory University School of Medicine, Atlanta, and colleagues studied whether therapy with granulocyte - macrophage colony stimulating factor (GM - CSF), an agent that functions as a white blood cell growth factor, would improve walking performance in patients with symptomatic peripheral artery disease (a form of vascular disease in which there is partial or total blockage of an artery, usually one leading to a leg or arm).

They also filled the tablet with GMC - SF (granulocyte macrophage colony - stimulating factor), an inflammatory protein known to attract immune cells.

Sargramostim is a form of GM - CSF (granulocyte - macrophage colony - stimulating factor), a natural protein that spurs the growth of white blood cells in the immune system.

Several of the viruses also release the gene for granulocyte - macrophage colony - stimulating factor (GM - CSF) an immune system protein.

Now, a study published online April 27th, in the Journal of Immunology, confirms that the cytokine GM - CSF (Granulocyte macrophage colony - stimulating factor) likely plays an important role in human disease and offers a new explanation for why the MS treatment interferon - Beta (INF - β) is often effective at reducing MS attacks.

Not exact matches

Jäger E, Ringhoffer M, Dienes HP, Arand M, Karbach J, Jäger D, Ilsemann C, Hagedorn M, Oesch F, Knuth A. Granulocyte - macrophage - colony - stimulating factor enhances immune responses to melanoma - associated peptides in vivo.

Molecular cloning of a complementary DNA encoding human macrophage - specific colony - stimulating factor (CSF - 1).

It has been observed for nearly 80 years that Bps can change colony morphology, and recent studies have shown an association between morphotypes and specificity for body compartments, ability to adhere and penetrate epithelial cells or macrophages, and expression of virulence factors.

Serial dilutions were plated on bacterial growth plates and colonies were counted after 24 h. For ex vivo infections, alveolar macrophages were harvested from BAL (N = 5) via differential plating and 4x104 macrophages were plated in 96 - well plates.

Recent studies on cartilage, which is found abundantly in homemade broth, show it supports the immune system in a variety of ways; it's a potent normalizer, true biological response modifier, activator of macrophages, activator of Natural Killer (NK) cells, rouser of B lymphocytes, and releaser of Colony Stimulating Factor.