Sentences with phrase «macrophage marker cd68»

Infiltrating cells in the myocardium and skeletal muscle were positive for the T - cell marker CD3 or the macrophage marker CD68.

Immunohistochemical analysis of perigonadal, perirenal, mesenteric, and subcutaneous adipose tissue revealed that the percentage of cells expressing the macrophage marker F4 / 80 (F4 / 80 +) was significantly and positively correlated with both adipocyte size and body mass.

«If the usefulness of these macrophage markers is established, it will be possible to evaluate kidney stone risk not only through inorganic but also some organic substances.

The accumulation of adipose tissue macrophages in direct proportion to adipocyte size and body mass may explain the coordinated increase in expression of genes encoding macrophage markers observed in our microarray expression data.

Among the three isolated cell populations, the relative gene expression of macrophage markers was highest among the F4 / 80 + cells.

The adipocyte - enriched population (gray bars) expressed small amounts of the macrophage markers (a), consistent with residual macrophage contamination seen by immunofluorescent staining of live cells (b).

Quantitative RT - PCR was used to measure the relative expression of macrophage markers (Emr1, Csf1r, Cd68) and an adipocyte - specific gene (Acrp30).

Not exact matches

The Discher Lab has since shown that a protein on human cells called CD47 functions as a «marker of self» by interacting with a protein on the surface of macrophages called SIRPA.

This latest study aimed to identify urinary M2 macrophage - associated markers, by performing multiplex urinalysis in individuals prone to developing calcium oxalate kidney stones.

To test whether adipose tissue F4 / 80 + cells shared a common bone marrow origin with other tissue macrophage populations, we transplanted bone marrow from C57BL / 6J mice expressing the CD45.1 leukocyte marker into 6 - week - old lethally irradiated C57BL / 6J mice expressing the CD45.2 leukocyte marker.

Macrophages are immune cells commonly used as markers for inflammation, and their increased presence helps confirm that SNRK plays a role in regulating inflammation in white fat tissue.

To identify and quantitate macrophages within adipose tissue, we immunohistochemically stained sections for the F4 / 80 antigen, a marker specific for mature macrophages (Figure 2; ref.

Hematopoietic malignancies were diagnosed using the following markers: for B - and T - lymphocyte detection, rat antimouse CD45R / B220 mAb (Southern Biotechnology Associates, Birmingham, AL; dilution 1:100); for T - lymphocyte detection, rabbit antihuman CD3 polyclonal antibody (Dako, Glostrup, Denmark; 1:100); and for monocyte / macrophage detection, rat antimouse F4 / 80 mAb (BMA Biomedicals AG, Augst, Switzerland; 1:20) and rat antimouse CD11b mAb (Chemicon International, Temecula, CA; 1:20).

Macrophages were identified by their typical morphology, as well as by their reactivity to the cell surface marker F4 / 80 (Fig. 2A) ⇓.

Increased expression of Cd11b - a marker of macrophages [38] seen with L - arginine admininistration in WNIN / Gr - Ob rats, might be due to increased influx of inflammatory cells in the exocrine fraction via adhesion molecules [17].

Conclusions: We validated (68) Ga - DOTATATE PET as a novel marker of atherosclerotic inflammation and confirmed that (68) Ga - DOTATATE offers superior coronary imaging, excellent macrophage specificity, and better power to discriminate high - risk versus low - risk coronary lesions than -LSB-(18) F] FDG.