Sentences with phrase «macrophage population»
"Macrophage population" refers to a group of immune cells called macrophages that are present in a particular area of the body. These cells play a vital role in defending our body against harmful substances, such as bacteria and viruses, by engulfing and destroying them. So, the phrase implies the total number or concentration of these immune cells in a specific location or within the body as a whole. Full definition
Research with mice has enabled the team of Michael Sieweke from the Centre d'Immunologie de Marseille - Luminy (CNRS / INSERM / Aix - Marseille University) to describe both testicular macrophage populations in depth.
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Steve Gerondakis and colleagues establish that Rel (from the c - rel gene) in mice is a positive or negative regulator of transcription in macrophages and that Rel has distinct roles in different macrophage populations.
Trapnell and Suzuki were prompted to test the novel macrophage transplantation therapy by studies showing that resident macrophage populations (such as those residing in the lung) can self - maintain without the cells having to regenerate directly from the bone marrow.
Separately, the high levels of a type of T cell called Th17 cells secrete gobs of interleukin - 17 (IL - 17), expanding macrophage populations.
To test whether adipose tissue F4 / 80 + cells shared a common bone marrow origin with other tissue macrophage populations, we transplanted bone marrow from C57BL / 6J mice expressing the CD45.1 leukocyte marker into 6 - week - old lethally irradiated C57BL / 6J mice expressing the CD45.2 leukocyte marker.
Mawhinney, L.A., * Thawer, S., Lu, W. - Y., van Roojen, N., Weaver, L.C., Brown, A. and Dekaban, G.A. Differential detection and distribution of microglial and hematogenous macrophage populations in the injured spinal cord of the lys - EGFP - ki transgenic mouse.
Each macrophage population has distinctive cellular markers.
Major limitation of our study was that we did not investigate the macrophage population from the respiratory tract of the mice with broncho alveolar lavage as we are certain that valuable information regarding our pre-treatment and treatment method would have been acquired.
«I think the key is the immune system needs to be balanced,» says Dhandapani, noting the seesaw effect on the macrophage population that happens following injury.