Sentences with phrase «macrophages taken»

mouse studies, macrophages taken from obese mice were less receptive to insulin than normal (in other words insulin resistant to a degree).

In the bone, macrophages take the form of osteoclasts — the cells responsible for the resorptive processes associated with continuous bone remodeling.

Dr Evanna Mills, who, with Dylan Ryan was joint first author of the work, said: «The macrophage takes the nutrient glucose, whose day job it is to provide energy, and surprisingly turns it into itaconate.

The macrophages take up iron particles injected into a patient's bloodstream and then migrate toward sites of inflammation.

Not exact matches

Ferumoxytol leaks out of blood vessels in areas of inflammation and is taken up by immune cells called macrophages, which congregate at sites of inflammation.

[Chinedu Nwokoro et al., «Inhaled black carbon in the lower airways of London cyclists»] Researchers at the London School of Medicine collected sputum samples from healthy non-smokers who walk or bike to see how much black carbon was in airway macrophages — a type of white blood cell that takes in foreign material.

The research team, Heller says, has already begun experiments to further explore the implications of these results, which include looking at differences in this pathway between cells taken from allergic and healthy individuals, and testing the efficacy of an inhalable drug that mimics the function of GRB1 and p70S6K to shut off the development of M2 macrophages in the lungs of mice.

Kemp and Payne have already used the tool to visualize the signaling process that takes place as macrophages discover bacteria and move to engulf and destroy the invaders.

Green tattoo pigment is taken up by dermal macrophages (left).

The team determined that the dead macrophages release the pigment into their surroundings, where, over the following weeks, it is taken up by new, monocyte - derived macrophages before it can disperse.

The pigment is released when these cells are killed (center) but, 90 days later, is taken back up into new macrophages that have replaced the old ones (right).

Claire E. Lewis and Munitta Muthana of the University of Sheffield in England and their colleagues have designed a drug delivery scheme that takes advantage of the natural attraction of macrophages to the oxygen - starved areas in tumors.

These investigations take advantage of white blood cells, monocytes, and macrophages that can target an inflammation site, including inside the brain.

To get around these safety concerns and to potentially maximize therapeutic effects on tumors, Alvey and colleagues took fresh, young macrophages from human donors as well as mouse donors and directly blocked their SIRPA.

The goal is to find new ways to tackle the disease, which requires a thorough understanding of how the bacterium, known as Mycobacterium tuberculosis, behaves once it takes hold of the macrophages in our lungs.

«Our new approach takes young and aggressive macrophages from the bone marrow of a human donor and removes a key safeguard that cancer cells have co-opted to prevent them from being engulfed,» Alvey said.

«Macrophages, the cells that engulf foreign particles and take them out of circulation, like to eat objects that don't require them to expand a lot,» says Mitragotri.

«We take blood cells called macrophages and put them with bacterial toxins,» explained Professor Grenier.

If these are within blood or skin, perhaps within macrophages [58], they could be taken up during the bloodmeal, but this has not been directly tested and is unlikely to be the case for greater than nine months post-treatment.

The bugs then take up residence inside cells of the immune system called macrophages.

Take away the macrophages and scar tissue formed.

Although macrophages, like dendritic cells, also take up antigens, they are more likely to degrade them than present them to T cells.

Atherosclerosis is initiated by high plasma cholesterol leading to monocyte entry into the artery wall and differentiation into macrophages, which take up lipoprotein cholesterol to become lipid engorged foam cells.

This immune activity takes the form of a TH1 dominant cellular response in which macrophages produce ILI, IL6, and TNFalpha, all of which have been shown to be elevated in the setting of depression.

The researchers took blood samples from Alzheimer's patients as well as healthy controls, then isolated important immune cells known as macrophages from the blood.

Immune cells (macrophages, monocytes, and lymphocytes) take charge, and a recurring, destructive process of tissue destruction and repair effort develops and continues until the source of the chronic inflammation is removed.

After the antibody binds to a dangerous molecule the macrophages consume the molecule, taking it out of circulation and destroying it.

These FA (fluorescent antibody) tests are particularly valuable in detecting coronavirus in the macrophages found in fluids withdrawn from sick cats or in tissue samples (usually taken after death).

«Reactive» Hepatitis: Diagnosed for unexplained liver enzyme activity; a term applied to liver biopsies lacking a distinct pattern but showing multifocal lipogranulomas (small clusters of macrophages (white blood cells that take in foreign matter.)

Wolfgang Streit, a neuroscientist at the University of Florida Brain Institute, reported that he and his team «took activated macrophages, put them in the injured spinal cord, and found enhanced regeneration.»