Sentences with phrase «macular dystrophy»
These mutations establish CMR as a novel animal model for Best macular dystrophy (BMD) in humans, an autosomal dominant, childhood retinal disease also caused by mutations in the Bestrophin gene [76, 77].
https://cgejournal.biomedcentral.com/
Twelve patients with Stargardt's Macular Dystrophy, which causes vision loss in children after the age of ten, will be enrolled in the combined Phase I / II (safety and effectiveness) clinical trial, announced Advanced Cell Technology of Marlborough, Mass..
«Using stem cells, we can generate a virtually unlimited supply of healthy (retinal) cells, which are the first cells to die off in (Stargardt's Macular Dystrophy) and other forms of macular degeneration.»
37 had macular dystrophy, a broader term for diseases affecting the macula, the central portion of the retina.
hESC - derived RPE were transplanted in four Asian patients: two with dry age - related macular degeneration and two with Stargardt's macular dystrophy.
In particular, widespread ocular diseases such as age - related macular degeneration (AMD) and retinitis pigmentosa (RP), as well as a genetic condition called Stargardt's macular dystrophy (STGD) that afflicts young people, are all potential disease targets for therapeutic approaches.
Advanced Cell Technology, a Santa Monica - based biotechnology company, is seeking FDA approval to use such derived cells to treat Stargardt's macular dystrophy, after studies in rats showed that the cells could restore vision.
A team led by Steven Schwartz at UCLA administered about 50,000 cells Tuesday into one eye of a volunteer suffering from Stargardt Macular Dystrophy, a progressive form of blindness that usually begins in childhood, and another with Dry Age - Related Macular Degeneration, the leading cause of blindness in the developed world, Advanced Cell Technology, which is sponsoring the study, announced Thursday.
Advanced Cell Technology is trying to treat Stargadt's Macular Dystrophy, a disease which affects 25,000 people in the US and can leave victims blinded as children.
Advanced Cell Technology (ACT), based in Marlborough, Mass., will begin testing its retinal cell treatment this year in a dozen patients with Stargardt's macular dystrophy, an inherited degenerative eye disease that leads to blindness in children.
This happens in age - related macular degeneration (AMD) and Stargardt macular dystrophy (SMD).
The treatment is for Stargardt's macular dystrophy, which affects 1 in 8000 people in the US.
Twelve people with Stargardt's macular dystrophy will be treated with retinal cells made from human embryonic stem cells (hESCs) in the hope of improving, or at least halting loss of sight.
Eye diseases — such as age - related macular degeneration, as well as a genetic condition called Stargardt's macular dystrophy that afflicts young people — are considered excellent candidates for stem cell therapy because the eye is an immune - privileged site, meaning transplanted cells are not as likely to be rejected as foreign compared with transplants elsewhere.
This happens in age - related macular degeneration and Stargardt's macular dystrophy.
The study included 18 patients, half with age - related macular degeneration and half with Stargardt's macular dystrophy, the leading causes of blindness in adults and juveniles.