Sentences with phrase «made by immune cells»

Mammals are known to fend off viruses with a system based on interferons, signaling proteins made by immune cells that amplify the body's attack on invaders.

Not exact matches

And a new analysis of the STEP trial, published last November in Proceedings of the National Academy of Sciences USA, provides a warning that the very vectors (adenoviruses, which are also employed in other vaccine development work) used to distribute the inactive HIV strains can actually make the immune system more vulnerable to infection by recruiting susceptible T cells to mucous membranes, where they are more likely to be infected during sexual activity.

By dissecting the heritage of these cells, we can find new targets to tackle a range of conditions including infectious diseases, cancers and immune disorders, and even make vaccines more effective.»

Blood from people affected by the 2014 Zika outbreak in French Polynesia provides the first evidence that the virus can make the immune system attack nerve cells

«Therefore, inhibiting NF - kB will might make tumor cells more vulnerable to elimination by the immune system.»

«Our immune system is made up of specialised cells that move through blood and tissue, preventing disease and fighting infection by distinguishing between what is the body's own healthy tissue and what is foreign.

In type 1 diabetes, beta cells in the pancreas that make insulin — the hormone that keeps our blood glucose levels at a safe concentration — are destroyed by the immune system.

Epigenetic therapies are thought to work in two ways to fix these errors in cancer cells — by correcting the «position» of the gene switches and by making the cell appear as though it's infected by a virus, triggering the immune system.

«We already know how to stimulate the immune system to make CD8 T cells by vaccination.

Further experiments suggested that the production of high levels of cell wall - associated GAG makes A. fumigatus more resistant than A. nidulans to neutrophil killing by neutrophil extracellular traps, or NETs (NETs are are networks of extracellular fibers, composed of DNA and proteins secreted by immune cells called neutrophils, that bind and trap various pathogens).

A close encounter with S. Typhimurium provokes an obvious response by the neutrophil: the initially round immune cell bulges out towards the bacterium, getting ready to make contact and ingest the intruder.

He and Clevers are trying to make the organoids resemble real cancer more closely by adding stroma and immune cells.

«By turning off the immune cells that would have protected them, the cancer cells make themselves uniquely vulnerable to the treatment,» Gravekamp says.

The findings made by IMBA scientists now provide evidence that one can find key molecular brakes in innate immune cells that, when modified, allow such cells to seek out and destroy metastatic tumors.

These proteins most closely resembled those made by endothelial cells in the lymphatic system, not the proteins made by macrophages or other immune cells.

«Ulcerative colitis is often associated with decreased mucus production and the worms seem to somehow restore mucus production, possibly by inducing a population of immune cells that make IL - 22,» Loke says.

Previous studies in the lab showed that once HCMV is inside the cell, it quickly becomes latent by entering the cell's nucleus and co-opting a cellular protein called Daxx — part of the intrinsic immune system — to shut down its own replication, the process of reproducing its genetic material to make more copies of itself.

Several previous studies have explored whether drugs can shock cells that are infected with latent HIV to make new viruses, setting them up for the kill by the natural immune response.

Tumors escape from the fighter T - cells that would otherwise attack them, by tricking the immune system and making an environment ripe for tumor growth.

The researchers, who were funded by Leukemia & Lymphoma Research and Cancer Research UK, have shown that some cancer cells are able to draw monoclonal antibodies inside themselves, making them invisible to immune cells.

They used the gene - editing CRISPR / Cas9 technique to sift the genomes of melanoma cells for changes that made tumors resistant to being killed by immune T cells, which are the main actors in the immune system response against infections and cancer cells.

Resolvins are made from an omega - 3 fatty acid by your immune cells.

The team identified chemicals released by bacteria that tell a new pair of lungs when to build immune cells, how many to make, and when to use them.

The Toxoplasma parasite does its dirty work by getting immune cells to make a chemical normally found in the brain

The studies, conducted separately on the East and West coasts of the United States, attempt to make the immune system resistant to HIV by crippling a receptor, known as CCR5, on T cells that the virus uses during the infection process.

The first to be tested was the gene for interleukin - 2, a messenger protein made by cells of the immune system.

Neoantigens are molecules on cell's surfaces that are produced by DNA mutations that are present in cancer cells but not in normal cells, making neoantigens ideal targets for immune therapy against cancer, say the scientists.

Since T cells can only recognize neoantigens that are «presented» to them by HLA molecules of the immune system, a key step in making the vaccine is using computer algorithms to predict which neoantigen peptides will bind strongly to the HLA molecules for recognition by T cells.

By contrast, the neoantigen vaccine is custom - made for each patient using antigens produced by mutations unique to the patient's cancer and only present on cancer cells, thus bypassing the nature immune tolerance procesBy contrast, the neoantigen vaccine is custom - made for each patient using antigens produced by mutations unique to the patient's cancer and only present on cancer cells, thus bypassing the nature immune tolerance procesby mutations unique to the patient's cancer and only present on cancer cells, thus bypassing the nature immune tolerance process.

With respect to biological applications, the group is focusing on how cellular heterogeneity and cell - to - cell communication drive ensemble - level decision - making in the immune system, with an emphasis on «two - body» interaction (e.g., host cell - virus interactions, innate immune control of adaptive immunity, tumor infiltration by immune cells).

They did this not only by trans - infection, but also by making the immune cells more prone to infection by HIV.

In future research supported by the National Institutes of Health, the researchers will study exactly how mucosal fibroblasts make immune cells more «infectable», which could ultimately lead to new targets for preventing HIV.

Four years ago several groups found that the body has two types of prostaglandin H2 synthase: an ever - ready PGHS - 1, present in nearly all cells for basic housekeeping duties, and PGHS - 2, made only as needed and just by those cells involved in inflammation and immune responses.

By studying the banana lectin molecule (top left) and what made it bind to both viruses and immune system cells (bottom left), the team was able to figure out how to change the way cells bind it, to make a new version (top right) that still binds viruses but doesn't cause inflammation (bottom right).

«Cells of the immune system communicate by passing small protein messages, and genetic studies have shown that different people will be predisposed to make different amounts of message, or even slightly different messages.

Some not - yet - identified molecule, or combination of molecules, such as proteins, fats, or sugars, made by bacteria cause the immune system to produce T helper 17 cells (Th17), which trigger a surge in inflammation as part of the response to a pathogenic strain.

If it does, then you might use the approach of making more beta cells right at early onset of the type 1 disease to try and stop or reverse the immune attack, making the immune system think its made a mistake, inducing something called anergy by making more beta cells.

The target of «atezo» is a molecule called PD - L1, which some cancer cells make to try to avoid being killed by the immune system.

The pluripotent stem cell process could allow researchers to make genetic changes to dampen or potentially eliminate the rejection of the pig islets by the human immune system.

At the University of Arizona, SENS Research Foundation is funding proof - of - concept research to restore the health of the immune system in aging mice, by simultaneously increasing the ability to produce new killer T - cells while making room for them by purging defective cells from the system.

Adoptive T cell transfer is an anticancer approach that enhances the natural cancer - fighting ability of the body's T cells by removing immune system cells, growing and / or making changes to them outside of the body, and then re-infusing them back into the patient.

Renowned for our work in beta cell production and research, we are conducting studies to expand and boost insulin - producing cells and make them less susceptible to attack by the immune system.

25.08.2015 Glycine rejuvenates old cells 24.08.2015 Diet with lots of vegetables reduces risk of mortality and cancer 22.08.2015 Camomile tea may help you live longer 20.08.2015 Flavonoids in food extend your life expectancy 15.08.2015 Red Blood Cell Width Distribution: another way in which resistance training extends life expectancy 06.05.2015 Strong muscles, strong immune system 27.03.2015 Delay aging by eating fewer meals per day 27.01.2015 Life extension, muscle tissue and irisin 25.01.2015 Meta - study: a high vitamin D level helps you live longer 24.01.2015 The more anabolic hormones your body produces, the longer you live 29.11.2014 Animal study: low - carb diet with lots of saturated fats cuts life expectancy 20.11.2014 Optimal fruit and veg intake is a pound a day, says meta - study 18.11.2014 Exercise prevents creakiness and illness in old age 19.09.2014 Live 12 percent longer on a low - glycaemic diet 13.09.2014 Elite athletes live longer 05.09.2014 Cacao extends your life expectancy and keeps you sharp 16.08.2014 Loneliness makes stress even more unhealthy 15.08.2014 High blood pressure?

Cytokines are proteins made by various types of white blood cells to turn on the immune system to attack invaders like:

Hashimoto's thyroiditis is characterized by the production of immune cells and autoantibodies by the body's immune system that can damage thyroid cells and compromise their ability to make thyroid hormone.

These immune cell surface proteins in themselves help the body by making our DNA less vulnerable to attack by our immune system which may have gone on the attack of foreign particles in our blood, such as dead cells, parasites, viruses, pollens and more.

Well, «they» may think they can make my sperm swim to the left, but little do they know that I have found the answer to making all of the world's citizens completely immune to toxins by virtue of the ultimate way to purge your cells and tissues of contaminated debris.

is an antioxidant that is used by the body to make Vitamin A, inhances the function of your immune system, protects your cells from the damaging effects of free radicals.

Believe it or not milk kefir make everything easier and my life better even with my t - lgl leukemia (an indolent not life threatening type of leukemia with low grade malignacy, most dangerous can be prove the lowering of immune system that caused by that and the low count of red cells).

Several other fascinating research studies on the healing properties of lemons and limes have shown that cell cycles — including the decision a cell makes about whether to divide (called mitosis) or die (apoptosis — are altered by lime juice, as are the activities of special immune cells called monocytes.