Sentences with phrase «made it to clinical»

«Despite huge efforts in the field of nanomedicine, fewer nanoparticle technologies than expected have made it to clinical trials.

But to date, only a handful of candidate compounds have made it to clinical trials, says Fenical.

However, due to ethical and application concerns, only recently have these cells made it to clinical trials.

Flaxseed has made it to clinical trials.

Not exact matches

In particular, the complaint alleges that throughout the Class Period, defendants made materially false and / or misleading statements and / or failed to disclose that (1) the trials for GED - 0301 suffered from fatal design defects, such that GED - 0301 had failed to demonstrate meaningful clinical efficacy; (2) the growth of Otezla sales had dramatically slowed during Celgene's third fiscal quarter of 2017; and (3) the clinical and nonclinical pharmacology data in Celgene's new drug application («NDA») for Ozanimod were insufficient to permit a complete review by the FDA, which resulted in the FDA issuing a refusal to file letter to Celgene regarding the NDA.

«So, are there things FDA can do to make sure that the dispensing of opioids more consistently reflects the clinical circumstances?»

Widespread adoption «requires a very rigorous economic and clinical analysis,» says Armen Bakirtzian, CEO and co-founder of Intellijoint Surgical, which makes a miniature surgical - grade tracking system that allows surgeons to select and align implants more accurately.

«Every pill gets approved based on very rigorous outcomes and clinical analysis, but it doesn't mean it gets bought — doctors make the decision, and they have to be convinced.»

On Thursday, the company announced it had struck 15 separate trade deals in China, one of the most notable being a partnership with Tencent Holdings to advance the use of artificial intelligence to support research and clinical decision making.

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

And the giant that makes the platform he's building on, Apple, for example, is running large - scale medical studies using its software, and is said to be looking to handle clinical data as the first step to a real attempt to break into the medical market.

While the researchers hope to use these findings in a clinical setting, they also seem to offer ready - made advice for those suffering from everyday levels of shyness.

First, founders Elad Benjamin, Eyal Toledano and Eyal Gura want to make their anonymized, indexed database of clinical records available to scientists as an open research tool.

Watchdog groups and transparency advocates say that it's important to have this information in hand to analyze whether or not the payments are linked to clinical decision - making.

Walmsley has been in place for around a year, but has already replaced nearly half of GSK's top executive team and has made sweeping changes in its R&D team, while shutting down many of its clinical drug trials in an effort to narrow the company's portfolio.

These efforts, along with advancements we're making in our strategy through building deeper clinical and local market capabilities, are moving us closer to our core objective of helping our members with their «whole health» so they can achieve their best health.»

Our range of clinical capabilities, resources and tools — such as in - home care, behavioral health, pharmacy services, data analytics and wellness solutions — combine to produce a simplified experience that makes health care easier to navigate and more effective.

This system, which currently has over 5 million Australians on it, could become a major tool for health providers to strengthen their decision making and care — they will have access to widespread clinical information such as discharge summaries, allergies, and medication usage.

All of that said, the NIH researchers did not go so far as to make a clinical recommendation; after all, 125 women is a small sample size.

On average about 99 % of all drugs in clinical trials never actually make it to approval, and drugs are still failing late - stage trials in 2017.

When it comes to mental wellness, the IEA determined that retirement makes a person about 40 percent more likely to suffer from clinical depression.

Through talking to experts in the field over the past year, Gates said he had identified five areas of need: Understanding better how Alzheimer's unfolds, detecting and diagnosing it earlier, pursuing multiple approaches to trying to halt the disease, making it easier for people to take part in clinical trials of potential new medicines, and using data better.

Though it's not a perfect treatment, Eli Lilly's solanezumab — a drug 15 years in the making — will pass muster in clinical tests and be well on its way to FDA approval, as a therapy for mild Alzheimer's, by year's end.

Granted, it makes sense that firms want to promote their technology platforms, drug candidates, and clinical trial results.

As I started thinking about how to change that, I became very focused on the laboratory space and the context of the power of laboratory data — which drives, some say, 80 % of clinical decisions — and the ability to help make access to that information more available to people, and to try to create actionable information that would be accessible to people at the time that it really matters.

«Sunlight will decrease the release of melatonin, a hormone that makes us sleepy,» says Steve Orma, clinical psychologist and co-author of Stop Worrying and Go to Sleep: How to Put Insomnia to Bed for Good.

However, in very rare circumstances, Ionis Pharmaceuticals is able to make an experimental drug that we are developing available for patients outside of a traditional clinical trial under an expanded access protocol, sometimes referred to as a treatment protocol.

Sanofi said gastrointestinal concerns have made its experimental GLP - 1 phase 2 drug SAR425899 «not acceptable for clinical use,» but it is undertaking new tests to...

By marrying innovative information technology, state - of - the - art measurement science, and insights from clinical experts, ArborMetrix helps clients make better decisions to optimize the quality and cost - efficiency of hospital and specialty care.

We bring together member, provider, and payer pharmacy case / care management staff with our own pharmacy and case / care management staff to facilitate the type of information sharing and decision - making that ultimately yields the best clinical and financial outcomes.

To accomplish optimal utilization of drug benefit, reduction in overall pharmacy costs, reduction in avoidable drug - impacted medical costs, and optimization of specialty spend, RxAdvance knows that it is critical to engage members, physicians, pharmacists, and plan sponsor's clinical / pharmacy staff in the decision - making procesTo accomplish optimal utilization of drug benefit, reduction in overall pharmacy costs, reduction in avoidable drug - impacted medical costs, and optimization of specialty spend, RxAdvance knows that it is critical to engage members, physicians, pharmacists, and plan sponsor's clinical / pharmacy staff in the decision - making procesto engage members, physicians, pharmacists, and plan sponsor's clinical / pharmacy staff in the decision - making process.

In response, Juno said, the FDA has asked the company to submit a Complete Response to the Clinical Hold consisting of a revised patient informed consent form, a revised investigator brochure, a revised trial protocol, and a copy of the presentation made to the agency yesterday.

To achieve this goal, several approaches are envisaged: identifying small populations with severe disease where a medicine's benefit - risk balance could be favorable; making more use of real - world data where appropriate to support clinical trial data; and involving health technology assessment bodies early in development to increase the chance that medicines will be recommended for payment and ultimately covered by national healthcare systemTo achieve this goal, several approaches are envisaged: identifying small populations with severe disease where a medicine's benefit - risk balance could be favorable; making more use of real - world data where appropriate to support clinical trial data; and involving health technology assessment bodies early in development to increase the chance that medicines will be recommended for payment and ultimately covered by national healthcare systemto support clinical trial data; and involving health technology assessment bodies early in development to increase the chance that medicines will be recommended for payment and ultimately covered by national healthcare systemto increase the chance that medicines will be recommended for payment and ultimately covered by national healthcare systems.

Insufficient access in remote health settings to simple, accurate and affordable diagnostic tests makes it difficult to provide timely, evidence - based clinical care.

«Through the intense focus our 285,000 colleagues bring to helping people live healthier lives and helping make the health system work better for everyone, we have grown to serve more people in more ways than ever, including through innovative uses of advanced technologies, data analytics, and modern clinical approaches that improve quality, lower cost and advance consumer and care provider satisfaction,» David S. Wichmann, CEO of UnitedHealth Group, said in a conference call.

Beginning in April 2018, Americares emergency planning specialists will be working with health care providers in Texas serving vulnerable populations to complete detailed after - action reports on the impact of Hurricane Harvey on their clinical operations and make recommendations for future performance.

The other teachers who are making a major contribution to educating person - centered ministers are the chaplain supervisors staffing the two hundred and fifty plus clinical pastoral education centers (accredited by the Association of Clinical Pastoral Education) Clinical training is, by far, the most important single learning experience available to a seminary student or mclinical pastoral education centers (accredited by the Association of Clinical Pastoral Education) Clinical training is, by far, the most important single learning experience available to a seminary student or mClinical Pastoral Education) Clinical training is, by far, the most important single learning experience available to a seminary student or mClinical training is, by far, the most important single learning experience available to a seminary student or minister.

The first literature that appeared as a result of the new movements, beginning with clinical training but not confined to it, made some use of the interview model although in a vague and diffuse fashion.

In actual practice clinical students often began by handling bedpans, were graduated either to making bedside calls or taking a patient for a walk.

It is curious that the early days of clinical pastoral education, which has done more than any other movement to foster the present knowledge and skill in pastoral care, actually relied only in part upon interviewing methods and yet made the interview image dominant as the ideal.

These clinical records sound like fairy - tales when one first reads them, yet it is impossible to doubt their accuracy; and, the path having been once opened by these first observers, similar observations have been made elsewhere.

Clinical experience has made it clear to me that there are several different Child sides from different stages of our early lives.

In a clinical setting this is very common amongst delusional patients trying to make relevant comparisons amongst random numbers or items.

Through combined experience in clinical nutrition, culinary training, and recipe development, we understand your goals and objectives and aim to make sure you meet them.

This strategic transaction allows Nestle to enter the fast - growing global market for clinical nutrition products tailor - made for people with inherited metabolic disorders.

«We chose to use Axiom Foods» Oryzatein ® ingredient,» said CEO of Growing Naturals, David Janow, «because it is the only 90 % brown rice protein isolate that is made with a proprietary enzyme fractioning method and was shown in a clinical trial for the first time to equal animal - based whey protein in building and maintaining muscle.»

His runs throw defenses into disarray, he can make great passes into the box, and his finishing is starting to become as clinical as before his injury crisis.

it seems obvious, theo is gone, he is tough on negotiation and demands and soft on delivering value, i like him, but if we sell and spend i am ok, as for danny, i thought he looked great v new castle, he was constantly stretching the defense, his track back was also great, heart and speed are there, takes a wenger to work on making him clinical, thats what arsene does best, teach.

He also has the ability to play striker and ATt mid, this makes him ideal as he will also be creative enough for arsenals left Poldi is clinical but lacks presence on the pitch in terms of contribution.

In turn, they will hope to be more clinical moving forward against top teams, otherwise they could be made to pay for their lack of edge in the final third.