Oligofructose even
made the obese mice less diabetic, but there was one thing the dietary supplement didn't change: body weight.
Not exact matches
A drug that reverses the condition in
obese mice could
make it much easier to control the disease
(Blaser's group reported earlier this month in Cell that giving
mice penicillin soon after birth changed their gut microbiome and
made them much more likely to be
obese as adults.)
Having an
obese grandfather can
make mice more likely to develop diabetes and other weight - related disorders, an effect that may be down to sperm epigenetics
The mechanism
making obese people have high blood pressure has been pinpointed in
mice, so we might be able to
make drugs to block it in humans
The news wasn't all bad: When Fischbach's team put
obese mice on a diet, their mammary fat tissue had fewer myofibroblasts, suggesting losing weight could
make a woman's fat tissue structure more normal and lower her breast cancer risk.
«TXN is especially potent in reducing insulin resistance in
mice made obese by feeding a high - fat diet,» said Cristobal Miranda, an associate professor at the Linus Pauling Institute who was involved in the research.
To
make their discovery, Jin and colleagues used both genetically
obese mice and
mice with diet - induced obesity as models.
Just 12 weeks of the high fat diet
made mice obese and diabetic, nearly doubling their body fat percentage compared to
mice fed a low fat, healthy diet.
In a study of
obese mice that received a diet rich in either coconut or safflower oil,
mice that received the coconut oil were found to have
made much less fat cells than
mice that received the safflower oil.
Researchers inject lab
mice, rats, or any kind of animal with MSG, which
makes them morbidly
obese.
The compound has been
making headlines since initial research showed that it helped
obese mice live longer, says James Smoliga, Ph.D., one of Baur's coauthors and an associate professor of physiology at High Point University, in High Point, N.C.
Gordon and his team found several years ago that genetically
obese mice (the animals lacked the ability to
make leptin, a hormone that limits appetite) had 50 percent fewer Bacteroidetes bacteria and 50 percent more Firmicutes bacteria than normal
mice did.