When exposed to a magnetic field, injected
magnetic nanoparticles heat up and cause neurons carrying a gene for heat sensitivity to fire (shown in yellow, white, green and light blue at right).
Not exact matches
Arnd Pralle, a physics researcher at the State University of New York at Buffalo, has developed a technique for employing
magnetic fields to
heat up
nanoparticles that have been implanted in neurons.
The
magnetic nanoparticles are excited by the applied field and begin to get hot,
heating and potentially destroying the surrounding cancer tissue.
Mice with cancer were placed in an alternating
magnetic field, causing
nanoparticles injected into a tumor to give out
heat and destroy it.
Once the virus infected neurons with the
heat - sensing gene, the researchers injected
magnetic nanoparticles into the same brain cells.
When they exposed the mouse to a
magnetic field, the
nanoparticles warmed up, and the now
heat - sensitive neurons fired.
A combination of iron - oxide
nanoparticles and an alternating
magnetic field, which together generate
heat, have activated an immune system response to tumors in mice according to an accepted manuscript by Dartmouth - Hitchcock Norris Cotton Center researchers in the journal Nanomedicine: Nanotechnology, Biology and Medicine released online on February 24, 2014.
Previous cancer studies had shown that by injecting tumors with
magnetic nanoparticles made of iron oxide — «essentially rust, with well - tuned
magnetic properties,» Anikeeva says — then exposing them to rapidly alternating
magnetic fields, excited
nanoparticles can be used to
heat and destroy cancer tumors while leaving surrounding, healthy tissue intact.
Researchers use
heated magnetic nanoparticles to manipulate nerve cells and control simple behavior in nematodes
Before injecting nematodes with
magnetic nanoparticles, the scientists first coated the manganese — iron
nanoparticles with polyethylene glycol, a molecule that targeted the particles to the mucus layer of the amphid region (an opening near the nematode's mouth that hosts the nerve cells involved in the
heat avoidance reflex).
«It's well known that you can inject
magnetic nanoparticles and
heat them up, so for me the nematode study is not as elegant as the earlier tests,» Dobson says.
A team of biophysicists from the State University of New York (S.U.N.Y.) at Buffalo used
magnetic nanoparticles to control
heat - activated protein gates called ion channels embedded in the membranes of nerve cells, allowing the researchers to stimulate a simple reflex in nematode worms at will.
A University of Manitoba physicist is part of an international research team developing a cancer treatment method that uses
magnetic nanoparticles to kill tumours with
heat.
The team used iron oxide for the core of the
nanoparticles, which not only enables the team to use them for
magnetic resonance imaging, but opens up possibilities in remote guidance and localized
magnetic heating to hasten the breaking up of the clots.
In the system,
nanoparticles injected into the brain convert a gentle, external
magnetic field into
heat, which triggers
heat - sensitive ion channels that have been genetically engineered into neurons.