A research
group led by Olga Malyshevskaya and Yoshihiro Urade of International Institute for Integrative Sleep Medicine (WPI - IIIS), University of Tsukuba, discovered that seizures, a life - threatening condition, can be induced by natural Δ9 - tetrahydrocannabinol (Δ9 - THC,
main constituent of marijuana) or the synthetic cannabinoid JWH - 018 (
main component of synthetic blend «Spice») in mice.