«Most of the signals that people are working with and identifying right now are the most abundant signals —
the main effector proteins,» says Klemke.
«And although synoviocytes are considered
the main effectors of cartilage damage in rheumatoid arthritis there's no therapy directed against them.»
Not exact matches
Among the multiple p53 transcriptional targets, p21 stands out as the
main, although not exclusive,
effector of p53 - mediated cell cycle arrest (8, 9, 10).
The adenosine A ₂ ₐ receptor is the
main adenosine receptor expressed on immune cell subsets including T - cells, NK cells and dendritic cells and binding of adenosine to the A ₂ ₐ receptor on immune cells blocks the activation and
effector functions of anti-tumor immune cells and promotes a regulatory, immune - suppressive phenotype.