Being unable to convert uric acid to allantoin is
the main predisposing factor to uric acid stone formation and accounts for why 80 % of uric acid bladder stones come from Dalmatians.
Not exact matches
In this review, I highlight the
main genes known to cause uncommon monogenic forms of diabetes (e.g. maturity - onset diabetes of the young — MODY — and insulin resistance syndromes), as well as describe some of the
main approaches used to identify genes involved in the more common forms of T2D that result from the interaction between environmental risk
factors and
predisposing genotypes.
Main outcome measures: Prevalence of self - reported smoking; predictors and patterns of smoking in early pregnancy; and relationships between smoking and the prevalence of
predisposing, enabling and reinforcing
factors, including women's knowledge about and attitudes towards smoking and the risks involved.