Completely blocking BACE1 in previous mouse models has resulted in
major brain defects, as the enzyme controls several fundamental developmental processes.
Not exact matches
Many children with congenital heart disease (CHD)-- the most common
major birth
defect in the United States — sustain
brain damage that often leads to problems with behavior, thinking, and learning.
Before pregnancy and during pregnancy, you need 400 micrograms of folic acid daily to help prevent
major birth
defects of the fetal
brain and spine called neural tube
defects.