Sentences with phrase «major cell classes»

Autism researchers from UCLA and Stanford will explore, among other things, forebrain spheroids, which contain the major cell classes of the developing forebrain.

The retina is the light detecting tissue of the eye, and consists of seven major cell classes.

Not exact matches

The elusive e-mailers, who claim to be part of a group called the Stem Cell Research Watch Group, responded to an e-mail from Science saying that they are «a group of students majoring in biology and often discuss papers that are taught in class.»

Major histocompatibility complex class II (MHC II) molecules capture peptides within the endocytic pathway to generate T cell receptor (TCR) ligands.

In this study, the SIgN team discovered for the first time that the integrity of p53 affects the production of a special cell surface protein called Major Histocompatibility Complex (MHC) class I. MHC class I molecules on the cancer cell surface serve as targets for the immune system.

Unlike CD8 + DCs that express the cell surface protein CD205, CD8 — DCs, which are positive for the 33D1 antigen, are specialized for presentation on major histocompatibility complex (MHC) class II.

When the team looked at what gene signatures the RORγt - dependent ILCs expressed, they found high expression of major histocompatibility complex class II (MHCII) protein, which some cells use to display foreign proteins to the immune system and directly interact with T cells.

The Purkinje cells, a class of neurons located in this region, are a major site of information integration that regulate changes in neural connections caused by varying factors such as behavior, environment, and emotions.

«These transplantation experiments confirmed that the reprogrammed cells indeed belong to cells of the intended brain regions and the progenitors produced the three major classes of neural cells: neurons, astrocytes and oligodendrocytes,» Zhang says.

Moretta A, Vitale M, Bottino C, Orengo AM, Morelli L, Augugliaro R, Barbaresi M, Ciccone E, Moretta L. P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells: anti-p58 antibodies reconstitute lysis of MHC class I - protected cells in NK clones displaying different specificities.

The other major class of immunotherapies are known as anti-CTLA-4 treatments, such as ipilimumab (Yervoy), which target a different mechanism to unleash immune cells to fight tumors.

The team concluded that AIG1 and ADTRP, at least in the cell types tested, appear to work mainly to break down FAHFAs and not any other major class of lipid.

In addition, we show that MAIT cells are selected and / or restricted by MR1, a monomorphic major histocompatibility complex class I - related molecule that is markedly conserved in diverse mammalian species.

Components of the major metazoan developmental signalling pathways, as well as classes of developmental transcription factors, are mostly present in Amphimedon and absent from Monosiga and other non-metazoan genomes13, 14,16,27,29, suggesting that ontogenetic development, including primary germ cell formation (Supplementary Note 8.4), originated on the metazoan stem3, 11,12.

Additionally, the proteasome regulates cell - cycle, antigen processing through class I major histocompatibility complex molecules, gene expression, and cell signaling (43).