27 percent reduction in conotruncal defects, or severe heart outflow tract
abnormalities; 23 percent reduction in coarctation of the aorta — a narrowing of the
major artery (the aorta) that carries blood to the body; 15 percent reduction in atrial and ventricular septal defects — holes in the wall separating heart chambers; however, no changes were seen with regard to chromosomally associated defects —
abnormality in the number of an infant's
chromosomes.