Sentences with phrase «major effector»

Yes ‐ associated protein (YAP) is a transcriptional co ‐ activator and major effector of the Hippo pathway, promoting cell proliferation and stemness.

Calmodulin (CaM) is a major effector for the intracellular actions of Ca2 + in nearly all cell types.

Not exact matches

Science magazine heralded these transcription activator - like effector nuclease proteins, known as TALENS, as a major scientific breakthrough in 2012, nicknaming them «genomic cruise missiles» for their ability to allow researchers to target specific locations with great efficiency.

Major areas of activity in our lab include 1) identification and characterization of Sgenes, 2) genomic analyses to identify the diversity of TAL effectors in pathogen populations and understand their evolution, and 3) structural and biochemical studies to better harness the unique properties of these proteins for applications such as targeted gene regulation and genome editing.